Gene description for NDUFA5
Gene name NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
Gene symbol NDUFA5
Other names/aliases B13
CI-13KD-B
CI-13kB
NUFM
UQOR13
Species Homo sapiens
 Database cross references - NDUFA5
ExoCarta ExoCarta_4698
Vesiclepedia VP_4698
Entrez Gene 4698
HGNC 7688
MIM 601677
UniProt Q16718  
 NDUFA5 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for NDUFA5
Molecular Function
    protein binding GO:0005515 IPI
    NADH dehydrogenase (ubiquinone) activity GO:0008137 NAS
Biological Process
    mitochondrial electron transport, NADH to ubiquinone GO:0006120 NAS
    aerobic respiration GO:0009060 NAS
    respiratory electron transport chain GO:0022904 IBA
    mitochondrial respiratory chain complex I assembly GO:0032981 IMP
    proton motive force-driven mitochondrial ATP synthesis GO:0042776 NAS
    proton transmembrane transport GO:1902600 IEA
Subcellular Localization
    mitochondrion GO:0005739 HTP
    mitochondrial inner membrane GO:0005743 IDA
    mitochondrial inner membrane GO:0005743 TAS
    respiratory chain complex I GO:0045271 IBA
    respiratory chain complex I GO:0045271 IDA
    respiratory chain complex I GO:0045271 NAS
 Experiment description of studies that identified NDUFA5 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for NDUFA5
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBE2H 7328
Affinity Capture-MS Homo sapiens
2 ATP6V1B2 526
Co-fractionation Homo sapiens
3 SLIRP 81892
Proximity Label-MS Homo sapiens
4 HDAC4  
Affinity Capture-MS Homo sapiens
5 CBX1 10951
Affinity Capture-MS Homo sapiens
6 BAG3 9531
Affinity Capture-MS Homo sapiens
7 RAB8A 4218
Affinity Capture-MS Homo sapiens
8 NDUFS1 4719
Co-fractionation Homo sapiens
9 COX15 1355
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
10 TTR 7276
Two-hybrid Homo sapiens
11 ADRB2  
Affinity Capture-MS Homo sapiens
12 TRUB2  
Proximity Label-MS Homo sapiens
13 MTG2  
Proximity Label-MS Homo sapiens
14 NGRN  
Proximity Label-MS Homo sapiens
15 PLEKHF2 79666
Two-hybrid Homo sapiens
16 CHCHD1  
Proximity Label-MS Homo sapiens
17 NDUFS7 374291
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 NDUFA4 4697
Affinity Capture-MS Homo sapiens
19 WDR26 80232
Affinity Capture-MS Homo sapiens
20 GCN1L1 10985
Co-fractionation Homo sapiens
21 MTRF1  
Proximity Label-MS Homo sapiens
22 GFM2 84340
Proximity Label-MS Homo sapiens
23 CCDC90B  
Proximity Label-MS Homo sapiens
24 LRPPRC 10128
Proximity Label-MS Homo sapiens
25 KIAA1429 25962
Affinity Capture-MS Homo sapiens
26 CAPZB 832
Affinity Capture-MS Homo sapiens
27 NDUFB9 4715
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
28 NDUFS3 4722
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
29 CRYZ 1429
Proximity Label-MS Homo sapiens
30 TFAM 7019
Proximity Label-MS Homo sapiens
31 PMPCA 23203
Proximity Label-MS Homo sapiens
32 COQ9  
Affinity Capture-MS Homo sapiens
33 C8orf82  
Proximity Label-MS Homo sapiens
34 NDUFA7 4701
Cross-Linking-MS (XL-MS) Homo sapiens
35 TIMMDC1  
Affinity Capture-MS Homo sapiens
36 HINT2 84681
Proximity Label-MS Homo sapiens
37 CHCHD10  
Affinity Capture-MS Homo sapiens
38 SLC25A12 8604
Proximity Label-MS Homo sapiens
39 POU5F1  
Affinity Capture-MS Homo sapiens
40 EWSR1 2130
Co-fractionation Homo sapiens
41 ABCE1 6059
Affinity Capture-MS Homo sapiens
42 SURF1  
Proximity Label-MS Homo sapiens
43 ATP5O 539
Co-fractionation Homo sapiens
44 EXD2  
Proximity Label-MS Homo sapiens
45 PHB 5245
Co-fractionation Homo sapiens
46 NDUFV3 4731
Affinity Capture-MS Homo sapiens
47 MRPS12  
Proximity Label-MS Homo sapiens
48 ATP5H 10476
Co-fractionation Homo sapiens
49 MECP2 4204
Affinity Capture-MS Homo sapiens
50 PMPCB 9512
Proximity Label-MS Homo sapiens
51 NDUFA11 126328
Affinity Capture-MS Homo sapiens
52 FASTKD2  
Proximity Label-MS Homo sapiens
53 VAPA 9218
Affinity Capture-MS Homo sapiens
54 NDUFS5 4725
Affinity Capture-MS Homo sapiens
55 MTERF3  
Proximity Label-MS Homo sapiens
56 MCCC2 64087
Co-fractionation Homo sapiens
57 NDUFB3 4709
Affinity Capture-MS Homo sapiens
58 RMND1 55005
Proximity Label-MS Homo sapiens
59 MDH2 4191
Proximity Label-MS Homo sapiens
60 KLF16  
Affinity Capture-MS Homo sapiens
61 APOO 79135
Proximity Label-MS Homo sapiens
62 JMJD6 23210
Affinity Capture-MS Homo sapiens
63 MTCH2 23788
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
64 C6orf203  
Proximity Label-MS Homo sapiens
65 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
66 FASTKD5  
Proximity Label-MS Homo sapiens
67 MRPS26 64949
Proximity Label-MS Homo sapiens
68 DNAJB8  
Affinity Capture-MS Homo sapiens
69 NDUFA8 4702
Co-fractionation Homo sapiens
70 TUFM 7284
Proximity Label-MS Homo sapiens
71 DIABLO 56616
Proximity Label-MS Homo sapiens
72 HSCB 150274
Proximity Label-MS Homo sapiens
73 CYB5A 1528
Co-fractionation Homo sapiens
74 CCDC109B 55013
Proximity Label-MS Homo sapiens
75 TBRG4 9238
Proximity Label-MS Homo sapiens
76 UQCRC1 7384
Co-fractionation Homo sapiens
77 MCU 90550
Proximity Label-MS Homo sapiens
78 MTFMT  
Proximity Label-MS Homo sapiens
79 MRPL11 65003
Proximity Label-MS Homo sapiens
80 MTRF1L  
Proximity Label-MS Homo sapiens
81 DNAJC30  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
82 VDAC2 7417
Co-fractionation Homo sapiens
83 ATP5B 506
Co-fractionation Homo sapiens
84 DMWD  
Affinity Capture-MS Homo sapiens
85 COX4I1 1327
Proximity Label-MS Homo sapiens
86 NDUFB5 4711
Affinity Capture-MS Homo sapiens
87 CISD3 284106
Affinity Capture-MS Homo sapiens
88 C15orf48  
Affinity Capture-MS Homo sapiens
89 SLC25A24 29957
Co-fractionation Homo sapiens
90 OTC 5009
Proximity Label-MS Homo sapiens
91 HADHB 3032
Co-fractionation Homo sapiens
92 MRRF  
Proximity Label-MS Homo sapiens
93 CANX 821
Co-fractionation Homo sapiens
94 MTIF2 4528
Proximity Label-MS Homo sapiens
95 NDUFB10 4716
Co-fractionation Homo sapiens
96 NDUFA13 51079
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
97 NDUFA9 4704
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
98 CLPP 8192
Proximity Label-MS Homo sapiens
99 MTIF3  
Proximity Label-MS Homo sapiens
100 UQCRC2 7385
Co-fractionation Homo sapiens
101 C2orf47  
Affinity Capture-MS Homo sapiens
102 GOLT1B 51026
Affinity Capture-MS Homo sapiens
103 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
104 COX6A1  
Co-fractionation Homo sapiens
105 DHX30 22907
Proximity Label-MS Homo sapiens
106 CORO1C 23603
Co-fractionation Homo sapiens
107 FN1 2335
Affinity Capture-MS Homo sapiens
108 AURKB 9212
Affinity Capture-MS Homo sapiens
109 C12orf65  
Proximity Label-MS Homo sapiens
110 MYCN  
Affinity Capture-MS Homo sapiens
111 SOAT1 6646
Affinity Capture-MS Homo sapiens
112 TACO1  
Proximity Label-MS Homo sapiens
113 MTG1  
Proximity Label-MS Homo sapiens
114 RPUSD4 84881
Proximity Label-MS Homo sapiens
115 MYC  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
116 COX6C 1345
Co-fractionation Homo sapiens
117 CCDC85B  
Two-hybrid Homo sapiens
118 RPL22 6146
Cross-Linking-MS (XL-MS) Homo sapiens
119 ACAD9 28976
Proximity Label-MS Homo sapiens
120 RCN2 5955
Co-fractionation Homo sapiens
121 VWA8 23078
Proximity Label-MS Homo sapiens
122 CLPB 81570
Proximity Label-MS Homo sapiens
123 VDAC1 7416
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
124 HSPA9 3313
Proximity Label-MS Homo sapiens
125 METTL15  
Proximity Label-MS Homo sapiens
126 DNAJC15  
Proximity Label-MS Homo sapiens
127 MCUR1 63933
Proximity Label-MS Homo sapiens
128 DAZAP2  
Two-hybrid Homo sapiens
129 APP 351
Reconstituted Complex Homo sapiens
130 DNAJC4  
Proximity Label-MS Homo sapiens
131 NDUFA1 4694
Affinity Capture-MS Homo sapiens
132 DNAJC28  
Proximity Label-MS Homo sapiens
133 CS 1431
Proximity Label-MS Homo sapiens
134 C17orf80 55028
Proximity Label-MS Homo sapiens
135 TSFM 10102
Proximity Label-MS Homo sapiens
136 AUH 549
Proximity Label-MS Homo sapiens
137 DNAJC19 131118
Proximity Label-MS Homo sapiens
138 ICT1 3396
Proximity Label-MS Homo sapiens
139 LONP1 9361
Proximity Label-MS Homo sapiens
140 DNAJA3 9093
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
141 SQSTM1 8878
Affinity Capture-MS Homo sapiens
142 C17orf89  
Affinity Capture-MS Homo sapiens
143 NDUFA12 55967
Affinity Capture-MS Homo sapiens
144 PDHB 5162
Co-fractionation Homo sapiens
145 NDUFB1 4707
Two-hybrid Homo sapiens
146 C21orf33  
Proximity Label-MS Homo sapiens
147 SSBP1 6742
Proximity Label-MS Homo sapiens
148 TMEM70  
Proximity Label-MS Homo sapiens
149 BABAM1 29086
Affinity Capture-MS Homo sapiens
150 FASTKD3  
Proximity Label-MS Homo sapiens
151 NDUFS8 4728
Co-fractionation Homo sapiens
152 GFM1 85476
Proximity Label-MS Homo sapiens
153 ARHGAP36  
Affinity Capture-MS Homo sapiens
154 TEFM  
Proximity Label-MS Homo sapiens
155 TOMM5  
Co-fractionation Homo sapiens
156 C19orf52  
Proximity Label-MS Homo sapiens
157 SLC25A51  
Proximity Label-MS Homo sapiens
158 RPUSD3  
Proximity Label-MS Homo sapiens
159 DHRS4 10901
Affinity Capture-MS Homo sapiens
160 GRSF1 2926
Proximity Label-MS Homo sapiens
161 C1QBP 708
Proximity Label-MS Homo sapiens
162 SERBP1 26135
Affinity Capture-MS Homo sapiens
163 NDUFAF4 29078
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
164 NDUFB11 54539
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
165 METTL17  
Proximity Label-MS Homo sapiens
166 NDUFS6  
Affinity Capture-MS Homo sapiens
167 DDX28  
Proximity Label-MS Homo sapiens
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