Gene description for RPL38
Gene name ribosomal protein L38
Gene symbol RPL38
Other names/aliases L38
Species Homo sapiens
 Database cross references - RPL38
ExoCarta ExoCarta_6169
Entrez Gene 6169
HGNC 10349
MIM 604182
UniProt P63173  
 RPL38 identified in exosomes derived from the following tissue/cell type
Squamous carcinoma cells 20124223    
 Gene ontology annotations for RPL38
Molecular Function
    RNA binding GO:0003723 TAS
    structural constituent of ribosome GO:0003735 NAS
Biological Process
    sensory perception of sound GO:0007605 IEA
    SRP-dependent cotranslational protein targeting to membrane GO:0006614 TAS
    viral transcription GO:0019083 TAS
    nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 TAS
    gene expression GO:0010467 TAS
    skeletal system development GO:0001501 IEA
    cellular protein metabolic process GO:0044267 TAS
    translational initiation GO:0006413 TAS
    middle ear morphogenesis GO:0042474 IEA
    viral life cycle GO:0019058 TAS
    90S preribosome assembly GO:0034463 IEA
    translation GO:0006412 TAS
    axial mesoderm development GO:0048318 IEA
    ossification GO:0001503 IEA
    viral process GO:0016032 TAS
    translational elongation GO:0006414 TAS
    regulation of translation GO:0006417 IEA
    translational termination GO:0006415 TAS
Subcellular Localization
    cytosolic large ribosomal subunit GO:0022625 IDA
    cytosol GO:0005829 TAS
    eukaryotic 80S initiation complex GO:0033291 IEA
    focal adhesion GO:0005925 IDA
 Experiment description of studies that identified RPL38 in exosomes
Experiment ID 191
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK.
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for RPL38
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 RIPK2  
Affinity Capture-MS Homo sapiens
2 TFE3  
Affinity Capture-MS Homo sapiens
3 NME2 4831
Affinity Capture-MS Homo sapiens
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