Gene description for CARM1
Gene name	coactivator-associated arginine methyltransferase 1
Gene symbol	CARM1
Other names/aliases	PRMT4
Species	Homo sapiens
Database cross references - CARM1
ExoCarta	ExoCarta_10498
Entrez Gene	10498
HGNC	23393
MIM	603934
UniProt	Q86X55
CARM1 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells	26054723
Hepatocytes	26054723

Gene ontology annotations for CARM1

Molecular Function     protein binding GO:0005515 IPI     beta-catenin binding GO:0008013 TAS     transcription coactivator activity GO:0003713 ISS     ligand-dependent nuclear receptor transcription coactivator activity GO:0030374 ISS     protein-arginine N-methyltransferase activity GO:0016274 ISS     histone methyltransferase activity GO:0042054 IDA     histone-arginine N-methyltransferase activity GO:0008469 IDA     protein methyltransferase activity GO:0008276 ISS     transcription regulatory region DNA binding GO:0044212 ISS     protein homodimerization activity GO:0042803 IEA     histone methyltransferase activity (H3-R17 specific) GO:0035642 ISS     protein-arginine omega-N asymmetric methyltransferase activity GO:0035242 ISS     lysine-acetylated histone binding GO:0070577 ISS Biological Process     regulation of transcription, DNA-templated GO:0006355 ISS     pathogenesis GO:0009405 IEA     regulation of growth plate cartilage chondrocyte proliferation GO:0003420 IEA     histone H3-R17 methylation GO:0034971 ISS     histone methylation GO:0016571 ISS     response to cAMP GO:0051591 IEA     chromatin organization GO:0006325 TAS     negative regulation of protein binding GO:0032091 IEA     transcription, DNA-templated GO:0006351 IEA     positive regulation of fat cell differentiation GO:0045600 ISS     small molecule metabolic process GO:0044281 TAS     cellular lipid metabolic process GO:0044255 TAS     viral process GO:0016032 IEA     regulation of intracellular estrogen receptor signaling pathway GO:0033146 ISS     endochondral bone morphogenesis GO:0060350 IEA     intracellular estrogen receptor signaling pathway GO:0030520 IEA     positive regulation of cell proliferation GO:0008284 IEA     histone H3-R2 methylation GO:0034970 IMP     peptidyl-arginine methylation, to asymmetrical-dimethyl arginine GO:0019919 IBA Subcellular Localization     cytosol GO:0005829 ISS     cytoplasm GO:0005737 IDA     nucleus GO:0005634 IDA     nucleoplasm GO:0005654 TAS