Gene description for KIF16B
Gene name kinesin family member 16B
Gene symbol KIF16B
Other names/aliases C20orf23
KISC20ORF
SNX23
Species Homo sapiens
 Database cross references - KIF16B
ExoCarta ExoCarta_55614
Vesiclepedia VP_55614
Entrez Gene 55614
HGNC 15869
UniProt Q96L93  
 KIF16B identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Mesenchymal stem cells 36408942    
 Gene ontology annotations for KIF16B
Molecular Function
    protein binding GO:0005515 IPI
    ATP binding GO:0005524 IEA
    phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547 IDA
    microtubule binding GO:0008017 IBA
    plus-end-directed microtubule motor activity GO:0008574 IBA
    plus-end-directed microtubule motor activity GO:0008574 IDA
    ATP hydrolysis activity GO:0016887 IBA
    phosphatidylinositol-3-phosphate binding GO:0032266 IDA
    phosphatidylinositol-3,4-bisphosphate binding GO:0043325 IDA
    phosphatidylinositol-3,5-bisphosphate binding GO:0080025 IDA
Biological Process
    formation of primary germ layer GO:0001704 ISS
    regulation of receptor recycling GO:0001919 IMP
    Golgi to endosome transport GO:0006895 ISS
    epidermal growth factor receptor signaling pathway GO:0007173 IMP
    endoderm development GO:0007492 ISS
    fibroblast growth factor receptor signaling pathway GO:0008543 ISS
    receptor catabolic process GO:0032801 IMP
    early endosome to late endosome transport GO:0045022 IMP
    vesicle transport along microtubule GO:0047496 IBA
Subcellular Localization
    cytoplasm GO:0005737 IBA
    cytoplasm GO:0005737 IDA
    endosome GO:0005768 IDA
    early endosome GO:0005769 IDA
    spindle GO:0005819 IDA
    cytosol GO:0005829 IEA
    kinesin complex GO:0005871 IBA
    microtubule GO:0005874 IBA
    early endosome membrane GO:0031901 IEA
 Experiment description of studies that identified KIF16B in exosomes
1
Experiment ID 489
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 488
MISEV standards
EM
Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for KIF16B
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 METTL7A 25840
Proximity Label-MS Homo sapiens
2 RAB9A 9367
Proximity Label-MS Homo sapiens
3 HSD17B11 51170
Proximity Label-MS Homo sapiens
4 ANKFY1 51479
Proximity Label-MS Homo sapiens
5 CPNE7 27132
Affinity Capture-MS Homo sapiens
6 S100P 6286
Affinity Capture-MS Homo sapiens
7 LAMTOR1 55004
Proximity Label-MS Homo sapiens
8 ITSN1 6453
Two-hybrid Homo sapiens
9 BAG2 9532
Affinity Capture-MS Homo sapiens
10 Fus  
Affinity Capture-MS Mus musculus
11 ARRDC4  
Affinity Capture-MS Homo sapiens
12 GAR1 54433
Affinity Capture-MS Homo sapiens
13 TP53 7157
Affinity Capture-MS Homo sapiens
14 Dctn1 13191
Affinity Capture-MS Mus musculus
15 LAMP3  
Proximity Label-MS Homo sapiens
16 RAB5A 5868
Proximity Label-MS Homo sapiens
17 PANX1 24145
Proximity Label-MS Homo sapiens
18 GJA1 2697
Proximity Label-MS Homo sapiens
19 NUP155 9631
Proximity Label-MS Homo sapiens
20 RAB4A 5867
Proximity Label-MS Homo sapiens
21 MON1B 22879
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 AURKA 6790
Affinity Capture-MS Homo sapiens
23 CCT8L2  
Affinity Capture-MS Homo sapiens
24 S100A2 6273
Affinity Capture-MS Homo sapiens
25 POLD1 5424
Affinity Capture-MS Homo sapiens
26 LCK 3932
Proximity Label-MS Homo sapiens
27 HSD3B7 80270
Proximity Label-MS Homo sapiens
28 NR3C1 2908
Proximity Label-MS Homo sapiens
29 SEPT10 151011
Proximity Label-MS Homo sapiens
30 LAMP2 3920
Proximity Label-MS Homo sapiens
31 HSPA8 3312
Affinity Capture-MS Homo sapiens
32 CXADR 1525
Proximity Label-MS Homo sapiens
33 ATG9A 79065
Proximity Label-MS Homo sapiens
34 HNRNPCL2 440563
Affinity Capture-MS Homo sapiens
35 OCIAD1 54940
Proximity Label-MS Homo sapiens
36 ANAPC2 29882
Proximity Label-MS Homo sapiens
37 DNAJC5 80331
Proximity Label-MS Homo sapiens
38 CARM1 10498
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
39 KIF1BP 26128
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 KRT8 3856
Proximity Label-MS Homo sapiens
41 RAB7A 7879
Proximity Label-MS Homo sapiens
42 RAB11A 8766
Proximity Label-MS Homo sapiens
43 CMTR1 23070
Affinity Capture-MS Homo sapiens
44 SPAG9 9043
Affinity Capture-MS Homo sapiens
45 PTPRN  
Affinity Capture-MS Homo sapiens
46 TXNIP 10628
Affinity Capture-MS Homo sapiens
47 DNAJC1 64215
Proximity Label-MS Homo sapiens
48 DHFRL1  
Proximity Label-MS Homo sapiens
49 PRKY  
Affinity Capture-MS Homo sapiens
50 RHOB 388
Proximity Label-MS Homo sapiens
51 CCZ1 51622
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
52 AMOT  
Proximity Label-MS Homo sapiens
53 ALOX5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
54 ENTHD2  
Affinity Capture-MS Homo sapiens
55 RHOT2 89941
Proximity Label-MS Homo sapiens
56 AKAP1 8165
Proximity Label-MS Homo sapiens
57 Magoh  
Affinity Capture-MS Mus musculus
58 SLC25A46 91137
Proximity Label-MS Homo sapiens
View the network image/svg+xml



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