Gene description for CMTR1
Gene name cap methyltransferase 1
Gene symbol CMTR1
Other names/aliases FTSJD2
KIAA0082
MTr1
hMTr1
Species Homo sapiens
 Database cross references - CMTR1
ExoCarta ExoCarta_23070
Vesiclepedia VP_23070
Entrez Gene 23070
HGNC 21077
MIM 616189
UniProt Q8N1G2  
 CMTR1 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for CMTR1
Molecular Function
    nucleic acid binding GO:0003676 IEA
    mRNA (nucleoside-2'-O-)-methyltransferase activity GO:0004483 IBA
    mRNA (nucleoside-2'-O-)-methyltransferase activity GO:0004483 IDA
Biological Process
    7-methylguanosine mRNA capping GO:0006370 IBA
    7-methylguanosine mRNA capping GO:0006370 IDA
    7-methylguanosine mRNA capping GO:0006370 IMP
    mRNA processing GO:0006397 IDA
    methylation GO:0032259 IEA
Subcellular Localization
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 IDA
    cytoplasm GO:0005737 IBA
    intracellular membrane-bounded organelle GO:0043231 IDA
 Experiment description of studies that identified CMTR1 in exosomes
1
Experiment ID 217
MISEV standards
EM
Biophysical techniques
TSG101|CD81|CD9|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CMTR1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CD3EAP  
Proximity Label-MS Homo sapiens
2 UBE2H 7328
Affinity Capture-MS Homo sapiens
3 KIF16B 55614
Affinity Capture-MS Homo sapiens
4 RIT1 6016
Negative Genetic Homo sapiens
5 GTSE1 51512
Affinity Capture-MS Homo sapiens
6 LDLRAD4  
Affinity Capture-MS Homo sapiens
7 SLX4  
Affinity Capture-MS Homo sapiens
8 ASF1A 25842
Proximity Label-MS Homo sapiens
9 PARP1 142
Proximity Label-MS Homo sapiens
10 WASF3 10810
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 LIG3 3980
Affinity Capture-MS Homo sapiens
12 TP53 7157
Affinity Capture-MS Homo sapiens
13 SETD3 84193
Co-fractionation Homo sapiens
14 PLAGL2  
Affinity Capture-MS Homo sapiens
15 LMNB1 4001
Proximity Label-MS Homo sapiens
16 IFNA8  
Affinity Capture-MS Homo sapiens
17 RPA2 6118
Co-fractionation Homo sapiens
18 HIST1H2BG 8339
Proximity Label-MS Homo sapiens
19 RPA1 6117
Co-fractionation Homo sapiens
20 EPB41L5 57669
Affinity Capture-MS Homo sapiens
21 BRDT  
Affinity Capture-MS Homo sapiens
22 VAPA 9218
Affinity Capture-MS Homo sapiens
23 TSC22D3  
Affinity Capture-MS Homo sapiens
24 CUL3 8452
Affinity Capture-MS Homo sapiens
25 C1orf35  
Affinity Capture-MS Homo sapiens
26 RNF20 56254
Co-fractionation Homo sapiens
27 SPATA1  
Affinity Capture-MS Homo sapiens
28 CCDC71  
Affinity Capture-MS Homo sapiens
29 MED17  
Affinity Capture-MS Homo sapiens
30 HNRNPCL2 440563
Affinity Capture-MS Homo sapiens
31 RNF40 9810
Co-fractionation Homo sapiens
32 MICU2 221154
Affinity Capture-MS Homo sapiens
33 APEX1 328
Proximity Label-MS Homo sapiens
34 MEIS2  
Affinity Capture-MS Homo sapiens
35 DDX23 9416
Proximity Label-MS Homo sapiens
36 RNF25 64320
Affinity Capture-MS Homo sapiens
37 TCF4  
Affinity Capture-MS Homo sapiens
38 IFNA1  
Affinity Capture-MS Homo sapiens
39 ZDHHC6  
Affinity Capture-MS Homo sapiens
40 RPA3 6119
Proximity Label-MS Homo sapiens
41 GTF2E2  
Affinity Capture-MS Homo sapiens
42 NTRK1 4914
Affinity Capture-MS Homo sapiens
43 CREB3L3  
Affinity Capture-MS Homo sapiens
44 EP300 2033
Affinity Capture-MS Homo sapiens
45 PTGES3 10728
Affinity Capture-MS Homo sapiens
46 KRAS 3845
Negative Genetic Homo sapiens
47 TMCC2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
48 NCAN  
Co-fractionation Homo sapiens
49 IARS 3376
Co-fractionation Homo sapiens
50 MEN1 4221
Affinity Capture-MS Homo sapiens
51 LMNA 4000
Proximity Label-MS Homo sapiens
52 TMEM69  
Affinity Capture-MS Homo sapiens
53 NELFE 7936
Affinity Capture-MS Homo sapiens
54 FAM133A 286499
Affinity Capture-MS Homo sapiens
55 PHGDH 26227
Cross-Linking-MS (XL-MS) Homo sapiens
56 SARNP 84324
Cross-Linking-MS (XL-MS) Homo sapiens
57 SP100 6672
Affinity Capture-MS Homo sapiens
58 EIF4B 1975
Co-fractionation Homo sapiens
View the network image/svg+xml
 Pathways in which CMTR1 is involved
No pathways found





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