Gene description for CMTR1
Gene name cap methyltransferase 1
Gene symbol CMTR1
Other names/aliases FTSJD2
KIAA0082
MTr1
hMTr1
Species Homo sapiens
 Database cross references - CMTR1
ExoCarta ExoCarta_23070
Entrez Gene 23070
HGNC 21077
MIM 616189
UniProt Q8N1G2  
 CMTR1 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for CMTR1
Molecular Function
    mRNA (nucleoside-2'-O-)-methyltransferase activity GO:0004483 IDA
    nucleic acid binding GO:0003676 IEA
Biological Process
    7-methylguanosine mRNA capping GO:0006370 IMP
    mRNA methylation GO:0080009 IDA
    cap1 mRNA methylation GO:0097309 IDA
Subcellular Localization
    cytoplasm GO:0005737 IDA
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 IDA
 Experiment description of studies that identified CMTR1 in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CMTR1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which CMTR1 is involved
No pathways found





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