Gene description for RPIA
Gene name ribose 5-phosphate isomerase A
Gene symbol RPIA
Other names/aliases RPI
RPIAD
Species Homo sapiens
 Database cross references - RPIA
ExoCarta ExoCarta_22934
Entrez Gene 22934
HGNC 10297
MIM 180430
UniProt P49247  
 RPIA identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for RPIA
Molecular Function
    monosaccharide binding GO:0048029 IEA
    ribose-5-phosphate isomerase activity GO:0004751 NAS
    protein binding GO:0005515 IPI
Biological Process
    pentose-phosphate shunt, non-oxidative branch GO:0009052 IEA
    small molecule metabolic process GO:0044281 TAS
    carbohydrate metabolic process GO:0005975 TAS
    pentose-phosphate shunt GO:0006098 TAS
Subcellular Localization
    intracellular membrane-bounded organelle GO:0043231 IEA
    cytosol GO:0005829 TAS
 Experiment description of studies that identified RPIA in exosomes
1
Experiment ID 217
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101
EV Cytosolic markers
✔
CD81|CD9|CD63
EV Membrane markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for RPIA
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 FLJ10204  
Two-hybrid Homo sapiens
2 RPIA 22934
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
3 STK16  
Two-hybrid Homo sapiens
4 FXR2 9513
Two-hybrid Homo sapiens
5 VTA1 51534
Two-hybrid Homo sapiens
6 LNX  
Two-hybrid Homo sapiens
7 NIF3L1 60491
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which RPIA is involved
PathwayEvidenceSource
Pentose phosphate pathway (hexose monophosphate shunt) TAS Reactome





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