Gene description for RPIA
Gene name ribose 5-phosphate isomerase A
Gene symbol RPIA
Other names/aliases RPI
RPIAD
Species Homo sapiens
 Database cross references - RPIA
ExoCarta ExoCarta_22934
Vesiclepedia VP_22934
Entrez Gene 22934
HGNC 10297
MIM 180430
UniProt P49247  
 RPIA identified in sEVs derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for RPIA
Molecular Function
    ribose-5-phosphate isomerase activity GO:0004751 EXP
    ribose-5-phosphate isomerase activity GO:0004751 IBA
    ribose-5-phosphate isomerase activity GO:0004751 NAS
    ribose-5-phosphate isomerase activity GO:0004751 TAS
    protein binding GO:0005515 IPI
    identical protein binding GO:0042802 IPI
    monosaccharide binding GO:0048029 IEA
Biological Process
    D-ribose metabolic process GO:0006014 IBA
    pentose-phosphate shunt GO:0006098 TAS
    pentose-phosphate shunt, non-oxidative branch GO:0009052 IBA
Subcellular Localization
    cytoplasm GO:0005737 IBA
    mitochondrion GO:0005739 HTP
    cytosol GO:0005829 TAS
 Experiment description of studies that identified RPIA in sEVs
1
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for RPIA
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ZRANB1 54764
Affinity Capture-MS Homo sapiens
2 TXN2 25828
Two-hybrid Homo sapiens
3 NOTCH2NL 388677
Affinity Capture-MS Homo sapiens
4 MARK4  
Affinity Capture-MS Homo sapiens
5 PTPN11 5781
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
6 SDCBP 6386
Two-hybrid Homo sapiens
7 TRPV5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 FANCD2  
Affinity Capture-MS Homo sapiens
9 CENPP  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
10 PCMT1 5110
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
11 C14orf119  
Two-hybrid Homo sapiens
12 AURKA 6790
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 DUSP3 1845
Affinity Capture-MS Homo sapiens
14 PAICS 10606
Co-fractionation Homo sapiens
15 CELF1 10658
Co-fractionation Homo sapiens
16 TXNRD1 7296
Co-fractionation Homo sapiens
17 EGFR 1956
Negative Genetic Homo sapiens
18 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
19 VTA1 51534
Two-hybrid Homo sapiens
20 DDIT4L  
Two-hybrid Homo sapiens
21 RNF208  
Two-hybrid Homo sapiens
22 NXF1 10482
Affinity Capture-RNA Homo sapiens
23 ERP44 23071
Affinity Capture-MS Homo sapiens
24 RPE  
Co-fractionation Homo sapiens
25 POTEE 445582
Affinity Capture-MS Homo sapiens
26 TKT 7086
Co-fractionation Homo sapiens
27 IGKC 3514
Affinity Capture-MS Homo sapiens
28 MOV10 4343
Affinity Capture-RNA Homo sapiens
29 LNX1  
Two-hybrid Homo sapiens
30 FXR2 9513
Two-hybrid Homo sapiens
31 FOXP2 93986
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
32 GORASP2 26003
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
33 DHH  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
34 CARM1 10498
Affinity Capture-MS Homo sapiens
35 ATPAF2 91647
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
36 WDR5B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
37 KRAS 3845
Negative Genetic Homo sapiens
38 RPIA 22934
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
39 IVNS1ABP  
Affinity Capture-MS Homo sapiens
40 GMPS 8833
Co-fractionation Homo sapiens
41 ST8SIA1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
42 STK16 8576
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
43 LHPP 64077
Affinity Capture-MS Homo sapiens
44 HSPB8 26353
Two-hybrid Homo sapiens
45 NIF3L1 60491
Two-hybrid Homo sapiens
46 MMAB 326625
Affinity Capture-MS Homo sapiens
47 PEPD 5184
Co-fractionation Homo sapiens
48 WDYHV1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
View the network image/svg+xml



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