Gene description for SMARCD1
Gene name SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
Gene symbol SMARCD1
Other names/aliases BAF60A
CRACD1
Rsc6p
Species Homo sapiens
 Database cross references - SMARCD1
ExoCarta ExoCarta_6602
Entrez Gene 6602
HGNC 11106
MIM 601735
UniProt Q96GM5  
 SMARCD1 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for SMARCD1
Molecular Function
    protein binding GO:0005515 IPI
    protein complex scaffold GO:0032947 IDA
    transcription coactivator activity GO:0003713 NAS
Biological Process
    nervous system development GO:0007399 IEA
    chromatin-mediated maintenance of transcription GO:0048096 IMP
    chromatin remodeling GO:0006338 IMP
    nucleosome disassembly GO:0006337 IDA
    regulation of transcription from RNA polymerase II promoter GO:0006357 NAS
Subcellular Localization
    nBAF complex GO:0071565 ISS
    SWI/SNF complex GO:0016514 IDA
    npBAF complex GO:0071564 ISS
 Experiment description of studies that identified SMARCD1 in exosomes
1
Experiment ID 217
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101
EV Cytosolic markers
✔
CD81|CD9|CD63
EV Membrane markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SMARCD1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 GATA1  
Reconstituted Complex Homo sapiens
2 LDOC1  
Two-hybrid Homo sapiens
3 SMARCC1 6599
Affinity Capture-Western Homo sapiens
4 DIPA  
Two-hybrid Homo sapiens
5 KRT15 3866
Two-hybrid Homo sapiens
6 NR1H4  
Reconstituted Complex Homo sapiens
7 SMARCA4 6597
Affinity Capture-Western Homo sapiens
8 KLF1  
Reconstituted Complex Homo sapiens
9 NR3C1 2908
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
10 FOS 2353
Affinity Capture-MS Homo sapiens
11 ING1  
Affinity Capture-MS Homo sapiens
12 USHBP1  
Two-hybrid Homo sapiens
13 NDP52  
Two-hybrid Homo sapiens
14 ESR1  
Reconstituted Complex Homo sapiens
15 BAZ1B 9031
Affinity Capture-MS Homo sapiens
16 PGR  
Reconstituted Complex Homo sapiens
17 SMARCC2 6601
Affinity Capture-Western Homo sapiens
View the network image/svg+xml
 Pathways in which SMARCD1 is involved
PathwayEvidenceSource
RMTs methylate histone arginines TAS Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here