Gene description for APOA5
Gene name	apolipoprotein A-V
Gene symbol	APOA5
Other names/aliases	APOAV RAP3
Species	Homo sapiens
Database cross references - APOA5
ExoCarta	ExoCarta_116519
Vesiclepedia	VP_116519
Entrez Gene	116519
HGNC	17288
MIM	606368
UniProt	Q6Q788
APOA5 identified in sEVs derived from the following tissue/cell type
Platelets	25332113
Platelets	25332113
Platelets	25332113

Gene ontology annotations for APOA5

Molecular Function     protein binding GO:0005515 IPI     phospholipid binding GO:0005543 IBA     phospholipid binding GO:0005543 IDA     enzyme activator activity GO:0008047 IDA     heparin binding GO:0008201 IDA     lipid binding GO:0008289 IDA     enzyme binding GO:0019899 IDA     phosphatidylcholine binding GO:0031210 IDA     lipase binding GO:0035473 IPI     low-density lipoprotein particle receptor binding GO:0050750 IPI     phosphatidylcholine-sterol O-acyltransferase activator activity GO:0060228 IBA     lipase activator activity GO:0060229 IMP     lipoprotein lipase activator activity GO:0060230 IDA     lipoprotein particle receptor binding GO:0070325 IPI     cholesterol transfer activity GO:0120020 IBA Biological Process     triglyceride metabolic process GO:0006641 IDA     triglyceride metabolic process GO:0006641 IMP     lipid transport GO:0006869 IDA     cholesterol metabolic process GO:0008203 IBA     positive regulation of triglyceride catabolic process GO:0010898 IDA     positive regulation of very-low-density lipoprotein particle remodeling GO:0010902 IDA     triglyceride catabolic process GO:0019433 IMP     cholesterol efflux GO:0033344 IBA     phospholipid efflux GO:0033700 IBA     triglyceride-rich lipoprotein particle remodeling GO:0034370 IEA     lipoprotein metabolic process GO:0042157 IEA     tissue regeneration GO:0042246 IEP     cholesterol homeostasis GO:0042632 IDA     positive regulation of fatty acid biosynthetic process GO:0045723 IDA     positive regulation of receptor-mediated endocytosis GO:0048260 TAS     positive regulation of lipid catabolic process GO:0050996 IDA     positive regulation of lipoprotein lipase activity GO:0051006 IDA     acylglycerol homeostasis GO:0055090 IBA     acylglycerol homeostasis GO:0055090 IDA     acylglycerol homeostasis GO:0055090 IMP     triglyceride homeostasis GO:0070328 IDA     triglyceride homeostasis GO:0070328 IMP Subcellular Localization     extracellular region GO:0005576 IDA     extracellular region GO:0005576 TAS     extracellular space GO:0005615 IDA     early endosome GO:0005769 IEA     late endosome GO:0005770 IEA     endoplasmic reticulum lumen GO:0005788 TAS     Golgi apparatus GO:0005794 IEA     very-low-density lipoprotein particle GO:0034361 IBA     very-low-density lipoprotein particle GO:0034361 IDA     low-density lipoprotein particle GO:0034362 IDA     high-density lipoprotein particle GO:0034364 IBA     high-density lipoprotein particle GO:0034364 IDA     chylomicron GO:0042627 IBA     chylomicron GO:0042627 IDA     extracellular vesicle GO:1903561 IBA