Gene description for APOA5
Gene name	apolipoprotein A-V
Gene symbol	APOA5
Other names/aliases	APOAV RAP3
Species	Homo sapiens
Database cross references - APOA5
ExoCarta	ExoCarta_116519
Vesiclepedia	VP_116519
Entrez Gene	116519
HGNC	17288
MIM	606368
UniProt	Q6Q788
APOA5 identified in exosomes derived from the following tissue/cell type
Platelets	25332113
Platelets	25332113
Platelets	25332113

Gene ontology annotations for APOA5

Molecular Function     lipase activator activity GO:0060229 IMP     enzyme activator activity GO:0008047 IDA     enzyme binding GO:0019899 IDA     phospholipid binding GO:0005543 IDA     lipase binding GO:0035473 IPI     phosphatidylcholine-sterol O-acyltransferase activator activity GO:0060228 IBA     lipoprotein lipase activator activity GO:0060230 IDA     low-density lipoprotein particle receptor binding GO:0050750 IPI     heparin binding GO:0008201 IDA     lipoprotein particle receptor binding GO:0070325 IPI     cholesterol binding GO:0015485 IBA     phosphatidylcholine binding GO:0031210 IDA     cholesterol transporter activity GO:0017127 IBA     lipid binding GO:0008289 IDA Biological Process     positive regulation of very-low-density lipoprotein particle remodeling GO:0010902 IDA     acylglycerol homeostasis GO:0055090 IMP     positive regulation of lipoprotein lipase activity GO:0051006 IDA     regulation of intestinal cholesterol absorption GO:0030300 IBA     lipid transport GO:0006869 IDA     cholesterol biosynthetic process GO:0006695 IBA     tissue regeneration GO:0042246 IEP     lipoprotein metabolic process GO:0042157 IBA     high-density lipoprotein particle assembly GO:0034380 IBA     positive regulation of cholesterol esterification GO:0010873 IBA     organ regeneration GO:0031100 IEA     very-low-density lipoprotein particle remodeling GO:0034372 IBA     phosphatidylcholine metabolic process GO:0046470 IBA     positive regulation of receptor-mediated endocytosis GO:0048260 TAS     positive regulation of lipid catabolic process GO:0050996 IDA     cholesterol efflux GO:0033344 IBA     reverse cholesterol transport GO:0043691 IBA     positive regulation of triglyceride catabolic process GO:0010898 IDA     triglyceride homeostasis GO:0070328 IMP     triglyceride metabolic process GO:0006641 IMP     phospholipid efflux GO:0033700 IBA     response to hormone GO:0009725 IEA     cholesterol homeostasis GO:0042632 IDA     positive regulation of fatty acid biosynthetic process GO:0045723 IDA     small molecule metabolic process GO:0044281 TAS     triglyceride catabolic process GO:0019433 IMP     cellular lipid metabolic process GO:0044255 TAS     neuron projection regeneration GO:0031102 IBA Subcellular Localization     extracellular space GO:0005615 IDA     very-low-density lipoprotein particle GO:0034361 IDA     chylomicron GO:0042627 IDA     low-density lipoprotein particle GO:0034362 IDA     extracellular region GO:0005576 TAS     high-density lipoprotein particle GO:0034364 IDA     blood microparticle GO:0072562 IBA