Gene description for P3H1
Gene name	prolyl 3-hydroxylase 1
Gene symbol	P3H1
Other names/aliases	GROS1 LEPRE1 OI8
Species	Homo sapiens
Database cross references - P3H1
ExoCarta	ExoCarta_64175
Entrez Gene	64175
HGNC	19316
MIM	610339
UniProt	Q32P28
P3H1 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells	Unpublished / Not applicable
Urine	19056867

Gene ontology annotations for P3H1

Molecular Function     L-ascorbic acid binding GO:0031418 IEA     collagen binding GO:0005518 ISS     iron ion binding GO:0005506 IEA     molecular_function GO:0003674 ND     procollagen-proline 3-dioxygenase activity GO:0019797 ISS     protein complex binding GO:0032403 ISS Biological Process     chaperone-mediated protein folding GO:0061077 ISS     collagen fibril organization GO:0030199 IEA     cell growth GO:0016049 IEA     extracellular matrix organization GO:0030198 TAS     negative regulation of post-translational protein modification GO:1901874 IMP     protein hydroxylation GO:0018126 IMP     regulation of ossification GO:0030278 IEA     regulation of protein secretion GO:0050708 IMP     protein folding GO:0006457 IMP     oxidation-reduction process GO:0055114 IEA     collagen metabolic process GO:0032963 ISS     bone development GO:0060348 IMP     negative regulation of cell proliferation GO:0008285 NAS     peptidyl-proline hydroxylation GO:0019511 ISS     protein stabilization GO:0050821 IMP Subcellular Localization     endoplasmic reticulum GO:0005783 IDA     extracellular exosome GO:0070062 IDA     nucleus GO:0005634 IEA     proteinaceous extracellular matrix GO:0005578 IEA     membrane GO:0016020 IDA     endoplasmic reticulum lumen GO:0005788 TAS     macromolecular complex GO:0032991 ISS