Gene description for SBNO1
Gene name strawberry notch homolog 1 (Drosophila)
Gene symbol SBNO1
Other names/aliases MOP3
Sno
Species Homo sapiens
 Database cross references - SBNO1
ExoCarta ExoCarta_55206
Vesiclepedia VP_55206
Entrez Gene 55206
HGNC 22973
MIM 614274
UniProt A3KN83  
 SBNO1 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for SBNO1
Molecular Function
    chromatin DNA binding GO:0031490 IBA
    histone binding GO:0042393 IBA
Biological Process
    regulation of DNA-templated transcription GO:0006355 IBA
Subcellular Localization
    nucleus GO:0005634 IBA
 Experiment description of studies that identified SBNO1 in exosomes
1
Experiment ID 237
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for SBNO1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CD3EAP  
Proximity Label-MS Homo sapiens
2 P3H1 64175
Co-fractionation Homo sapiens
3 RIT1 6016
Negative Genetic Homo sapiens
4 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
5 ZBTB2 57621
Affinity Capture-MS Homo sapiens
6 CHD3 1107
Co-fractionation Homo sapiens
7 ACRBP  
Affinity Capture-MS Homo sapiens
8 MSH6 2956
Co-fractionation Homo sapiens
9 MED17  
Affinity Capture-MS Homo sapiens
10 TP53 7157
Affinity Capture-MS Homo sapiens
11 HSPA8 3312
Affinity Capture-MS Homo sapiens
12 USP15 9958
Affinity Capture-MS Homo sapiens
13 TM9SF3 56889
Cross-Linking-MS (XL-MS) Homo sapiens
14 SSRP1 6749
Co-fractionation Homo sapiens
15 UBR4 23352
Co-fractionation Homo sapiens
16 IVNS1ABP  
Affinity Capture-MS Homo sapiens
17 HIST1H2BG 8339
Proximity Label-MS Homo sapiens
18 SUB1 10923
Co-fractionation Homo sapiens
19 MEN1 4221
Affinity Capture-MS Homo sapiens
20 PRKAR1A 5573
Affinity Capture-MS Homo sapiens
21 PBDC1 51260
Co-fractionation Homo sapiens
22 HIST1H2BC 8347
Cross-Linking-MS (XL-MS) Homo sapiens
23 ZNF444  
Affinity Capture-MS Homo sapiens
24 CEACAM16  
Affinity Capture-MS Homo sapiens
25 SMAD4  
Affinity Capture-MS Homo sapiens
26 EGFR 1956
Negative Genetic Homo sapiens
27 HIST1H2BD 3017
Cross-Linking-MS (XL-MS) Homo sapiens
28 MCM4 4173
Affinity Capture-MS Homo sapiens
29 SRSF2 6427
Co-fractionation Homo sapiens
30 MILR1  
Affinity Capture-MS Homo sapiens
31 RTN4 57142
Co-fractionation Homo sapiens
32 GTF3C4 9329
Affinity Capture-MS Homo sapiens
33 GSK3A 2931
Two-hybrid Homo sapiens
34 CBX3 11335
Proximity Label-MS Homo sapiens
35 PRMT5 10419
Co-fractionation Homo sapiens
36 NUP50 10762
Proximity Label-MS Homo sapiens
37 ARL6 84100
Affinity Capture-MS Homo sapiens
38 C12orf49  
Negative Genetic Homo sapiens
39 ACTR3B 57180
Affinity Capture-MS Homo sapiens
40 RPA2 6118
Proximity Label-MS Homo sapiens
41 BBS1 582
Affinity Capture-MS Homo sapiens
42 WDYHV1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
43 NTRK1 4914
Affinity Capture-MS Homo sapiens
44 MCM2 4171
Affinity Capture-MS Homo sapiens
45 SPAG9 9043
Affinity Capture-MS Homo sapiens
46 SEC24C 9632
Co-fractionation Homo sapiens
47 ANKRD49  
Affinity Capture-MS Homo sapiens
48 PTGES3 10728
Affinity Capture-MS Homo sapiens
49 KRAS 3845
Negative Genetic Homo sapiens
50 RBM25 58517
Co-fractionation Homo sapiens
51 MCM6 4175
Affinity Capture-MS Homo sapiens
52 RPA3 6119
Proximity Label-MS Homo sapiens
53 EPS15L1 58513
Affinity Capture-MS Homo sapiens
54 EP300 2033
Affinity Capture-MS Homo sapiens
55 SLX4  
Affinity Capture-MS Homo sapiens
56 HSPA2 3306
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which SBNO1 is involved
No pathways found





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