Gene description for Sod1
Gene name	superoxide dismutase 1, soluble
Gene symbol	Sod1
Other names/aliases	B430204E11Rik Cu/Zn-SOD CuZnSOD Ipo-1 Ipo1 SODC Sod-1
Species	Mus musculus
Database cross references - Sod1
ExoCarta	ExoCarta_20655
Entrez Gene	20655
UniProt	P08228
Sod1 identified in exosomes derived from the following tissue/cell type
Mast cells	17486113

Gene ontology annotations for Sod1

Molecular Function     Rac GTPase binding GO:0048365 ISO     protein binding GO:0005515 IPI     metal ion binding GO:0046872 IEA     copper ion binding GO:0005507 ISO     antioxidant activity GO:0016209 IEA     protein phosphatase 2B binding GO:0030346 ISO     superoxide dismutase activity GO:0004784 TAS     oxidoreductase activity GO:0016491 IEA     chaperone binding GO:0051087 ISO     identical protein binding GO:0042802 ISO     enzyme binding GO:0019899 ISO     zinc ion binding GO:0008270 ISO Biological Process     response to drug GO:0042493 IMP     transmission of nerve impulse GO:0019226 IMP     reactive oxygen species metabolic process GO:0072593 ISO     superoxide anion generation GO:0042554 IDA     spermatogenesis GO:0007283 IMP     response to reactive oxygen species GO:0000302 IMP     myeloid cell homeostasis GO:0002262 IMP     response to heat GO:0009408 IMP     hydrogen peroxide biosynthetic process GO:0050665 ISO     regulation of GTPase activity GO:0043087 ISO     muscle cell cellular homeostasis GO:0046716 IMP     activation of MAPK activity GO:0000187 IDA     positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway GO:1902177 ISO     superoxide metabolic process GO:0006801 ISO     positive regulation of cytokine production GO:0001819 ISO     response to hydrogen peroxide GO:0042542 IMP     embryo implantation GO:0007566 IMP     neurofilament cytoskeleton organization GO:0060052 IMP     cellular iron ion homeostasis GO:0006879 IMP     regulation of multicellular organism growth GO:0040014 IMP     retrograde axon cargo transport GO:0008090 IMP     auditory receptor cell stereocilium organization GO:0060088 IMP     sensory perception of sound GO:0007605 IMP     cell aging GO:0007569 ISO     heart contraction GO:0060047 ISO     response to copper ion GO:0046688 ISO     response to oxidative stress GO:0006979 ISO     positive regulation of catalytic activity GO:0043085 ISO     removal of superoxide radicals GO:0019430 TAS     negative regulation of cholesterol biosynthetic process GO:0045541 ISO     response to nutrient levels GO:0031667 ISO     locomotory behavior GO:0007626 IMP     glutathione metabolic process GO:0006749 IMP     peripheral nervous system myelin maintenance GO:0032287 IMP     positive regulation of superoxide anion generation GO:0032930 ISO     relaxation of vascular smooth muscle GO:0060087 IMP     regulation of mitochondrial membrane potential GO:0051881 ISO     negative regulation of neuron apoptotic process GO:0043524 IMP     response to organic substance GO:0010033 ISO     aging GO:0007568 IMP     retina homeostasis GO:0001895 IMP     response to axon injury GO:0048678 IMP     response to ethanol GO:0045471 IMP     oxidation-reduction process GO:0055114 IMP     anterograde axon cargo transport GO:0008089 IMP     ovarian follicle development GO:0001541 IMP     regulation of blood pressure GO:0008217 IMP     regulation of protein kinase activity GO:0045859 ISO     negative regulation of apoptotic process GO:0043066 ISO     response to superoxide GO:0000303 ISO Subcellular Localization     mitochondrial intermembrane space GO:0005758 ISO     dendrite cytoplasm GO:0032839 ISO     secretory granule GO:0030141 ISO     dense core granule GO:0031045 ISO     myelin sheath GO:0043209 IDA     intracellular GO:0005622 IMP     mitochondrion GO:0005739 ISO     nucleus GO:0005634 ISO     cytoplasm GO:0005737 TAS     neuronal cell body GO:0043025 ISO     neuron projection GO:0043005 ISO     cytosol GO:0005829 ISO     protein complex GO:0043234 ISO     extracellular matrix GO:0031012 ISO     peroxisome GO:0005777 ISO     cell GO:0005623 IMP     cytoplasmic vesicle GO:0031410 ISO     extracellular exosome GO:0070062 ISO     nucleoplasm GO:0005654 ISO     plasma membrane GO:0005886 ISO     lysosome GO:0005764 ISO     extracellular region GO:0005576 ISO     extracellular space GO:0005615 ISO