Gene description for KIF21B
Gene name kinesin family member 21B
Gene symbol KIF21B
Other names/aliases -
Species Homo sapiens
 Database cross references - KIF21B
ExoCarta ExoCarta_23046
Entrez Gene 23046
HGNC 29442
MIM 608322
UniProt O75037  
 KIF21B identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for KIF21B
Molecular Function
    ATPase activity GO:0016887 IBA
    microtubule motor activity GO:0003777 IBA
    microtubule binding GO:0008017 IEA
    ATP binding GO:0005524 IEA
Biological Process
    metabolic process GO:0008152 IEA
    microtubule-based movement GO:0007018 IBA
Subcellular Localization
    microtubule GO:0005874 IEA
    cytoplasm GO:0005737 IEA
    kinesin complex GO:0005871 IBA
 Experiment description of studies that identified KIF21B in exosomes
Experiment ID 237
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for KIF21B
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which KIF21B is involved
No pathways found

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