Gene description for GCC1
Gene name GRIP and coiled-coil domain containing 1
Gene symbol GCC1
Other names/aliases GCC1P
GCC88
Species Homo sapiens
 Database cross references - GCC1
ExoCarta ExoCarta_79571
Vesiclepedia VP_79571
Entrez Gene 79571
HGNC 19095
MIM 607418
UniProt Q96CN9  
 GCC1 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
 Gene ontology annotations for GCC1
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    protein targeting to Golgi GO:0000042 IEA
Subcellular Localization
    cytoplasm GO:0005737 IDA
    Golgi membrane GO:0000139 IEA
    plasma membrane GO:0005886 IDA
    Golgi apparatus GO:0005794 IDA
 Experiment description of studies that identified GCC1 in exosomes
1
Experiment ID 488
MISEV standards
EM
EV Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
EV Enriched markers
CANX
EV Negative markers
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for GCC1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 DIPA  
Two-hybrid Homo sapiens
2 AMOTL2 51421
Two-hybrid Homo sapiens
3 KIAA1217 56243
Two-hybrid Homo sapiens
4 CPSF7 79869
Two-hybrid Homo sapiens
5 KIAA0980  
Two-hybrid Homo sapiens
6 USHBP1  
Two-hybrid Homo sapiens
7 ARL1 400
Two-hybrid Homo sapiens
8 FBF1  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
9 TRIM29 23650
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
View the network image/svg+xml
 Pathways in which GCC1 is involved
No pathways found





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