Experiment description of studies that identified KIAA1217 in exosomes

1 Experiment ID 224 MISEV standards ✔ EM|AFM Biophysical techniques ✔ Alix|TSG101|CD63|CD81 Enriched markers ✔ GOLGA2 Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25944692     Organism Homo sapiens Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S" Journal name Oncotarget Publication year 2015 Sample Neuroblastoma cells Sample name SH-SY5Y Isolation/purification methods Differential centrifugation Ultracentrifugation OptiPrep density gradient Flotation density 1.10 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting

Protein-protein interactions for KIAA1217

Protein Interactor ExoCarta ID Identification method PubMed Species 1 SIAH1   Two-hybrid Homo sapiens 2 PCM1 5108 Proximity Label-MS Homo sapiens 3 KRT18 3875 Proximity Label-MS Homo sapiens 4 RNF43   Proximity Label-MS Homo sapiens 5 LYN 4067 Proximity Label-MS Homo sapiens 6 HSPA5 3309 Cross-Linking-MS (XL-MS) Homo sapiens 7 KRT27 342574 Two-hybrid Homo sapiens 8 MAPRE1 22919 Proximity Label-MS Homo sapiens Affinity Capture-MS Homo sapiens 9 ABI1 10006 Two-hybrid Homo sapiens 10 TRAF2 7186 Two-hybrid Homo sapiens 11 WASF3 10810 Affinity Capture-MS Homo sapiens 12 ALKBH7 84266 Two-hybrid Homo sapiens 13 PXN 5829 Proximity Label-MS Homo sapiens 14 EXOC8 149371 Two-hybrid Homo sapiens 15 XPO1 7514 Affinity Capture-MS Homo sapiens 16 VPS52 6293 Two-hybrid Homo sapiens 17 RAB4A 5867 Proximity Label-MS Homo sapiens 18 PFN1 5216 Proximity Label-MS Homo sapiens 19 PARD3 56288 Proximity Label-MS Homo sapiens 20 EPB41L4A 64097 Proximity Label-MS Homo sapiens 21 CTNNB1 1499 Proximity Label-MS Homo sapiens 22 TEX11   Two-hybrid Homo sapiens 23 LCK 3932 Proximity Label-MS Homo sapiens 24 HSBP1 3281 Two-hybrid Homo sapiens 25 BTF3 689 Affinity Capture-MS Homo sapiens 26 PRPH 5630 Proximity Label-MS Homo sapiens 27 EGFR 1956 Affinity Capture-MS Homo sapiens 28 MAPRE3   Proximity Label-MS Homo sapiens 29 SHMT2 6472 Affinity Capture-RNA Homo sapiens 30 GJA1 2697 Proximity Label-MS Homo sapiens 31 TRIB2 28951 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 32 SOX2   Affinity Capture-MS Homo sapiens 33 LATS1   Proximity Label-MS Homo sapiens 34 NCK2 8440 Two-hybrid Homo sapiens 35 MICU2 221154 Affinity Capture-MS Homo sapiens 36 GOLGA2 2801 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 37 PTK6   Two-hybrid Homo sapiens 38 KRT15 3866 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 39 ABI2 10152 Two-hybrid Homo sapiens Two-hybrid Homo sapiens Two-hybrid Homo sapiens 40 KDM1A 23028 Proximity Label-MS Homo sapiens 41 CDH1 999 Proximity Label-MS Homo sapiens 42 EPHA2 1969 Proximity Label-MS Homo sapiens 43 MLLT4 4301 Proximity Label-MS Homo sapiens 44 IMPDH2 3615 Proximity Label-MS Homo sapiens 45 FXR2 9513 Two-hybrid Homo sapiens 46 DYRK1A 1859 Affinity Capture-MS Homo sapiens 47 HNRNPLL 92906 Co-fractionation Homo sapiens 48 FLOT1 10211 Proximity Label-MS Homo sapiens 49 RINT1 60561 Two-hybrid Homo sapiens 50 SEC16A 9919 Affinity Capture-MS Homo sapiens 51 LIPA 3988 Co-fractionation Homo sapiens 52 EXOSC5 56915 Two-hybrid Homo sapiens 53 DCTN1 1639 Proximity Label-MS Homo sapiens 54 NDC80 10403 Proximity Label-MS Homo sapiens 55 SORBS3 10174 Two-hybrid Homo sapiens 56 BICD2 23299 Proximity Label-MS Homo sapiens 57 ANK3   Proximity Label-MS Homo sapiens 58 GCC1 79571 Two-hybrid Homo sapiens 59 STIL   Proximity Label-MS Homo sapiens 60 AR 367 Affinity Capture-MS Homo sapiens 61 KRAS 3845 Proximity Label-MS Homo sapiens 62 CTNNA1 1495 Proximity Label-MS Homo sapiens 63 MYC   Affinity Capture-MS Homo sapiens 64 NARS 4677 Co-fractionation Homo sapiens 65 NINL   Proximity Label-MS Homo sapiens 66 INCA1   Two-hybrid Homo sapiens 67 RPA3 6119 Proximity Label-MS Homo sapiens 68 RHOT2 89941 Proximity Label-MS Homo sapiens 69 FHL2 2274 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 70 NIN 51199 Proximity Label-MS Homo sapiens 71 TRAF1 7185 Two-hybrid Homo sapiens View the network

Pathways in which KIAA1217 is involved

No pathways found