Gene description for KIAA1217
Gene name KIAA1217
Gene symbol KIAA1217
Other names/aliases SKT
Species Homo sapiens
 Database cross references - KIAA1217
ExoCarta ExoCarta_56243
Entrez Gene 56243
HGNC 25428
UniProt Q5T5P2  
 KIAA1217 identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells 25944692    
 Gene ontology annotations for KIAA1217
Molecular Function
    protein binding GO:0005515 IPI
    molecular_function GO:0003674 ND
Biological Process
    embryonic skeletal system development GO:0048706 ISS
Subcellular Localization
    cytoplasm GO:0005737 ISS
 Experiment description of studies that identified KIAA1217 in exosomes
Experiment ID 224
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for KIAA1217
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SORBS3 10174
Two-hybrid Homo sapiens
2 GCC1  
Two-hybrid Homo sapiens
3 TEX11  
Two-hybrid Homo sapiens
4 KRT15 3866
Two-hybrid Homo sapiens
5 NCK2 8440
Two-hybrid Homo sapiens
6 FXR2 9513
Two-hybrid Homo sapiens
7 EXOSC5 56915
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which KIAA1217 is involved
No pathways found

Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here