Gene description for ZC4H2
Gene name zinc finger, C4H2 domain containing
Gene symbol ZC4H2
Other names/aliases HCA127
KIAA1166
WRWF
WWS
Species Homo sapiens
 Database cross references - ZC4H2
ExoCarta ExoCarta_55906
Entrez Gene 55906
HGNC 24931
MIM 300897
UniProt Q9NQZ6  
 ZC4H2 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for ZC4H2
Molecular Function
    metal ion binding GO:0046872 IEA
    protein binding GO:0005515 IPI
Biological Process
    nervous system development GO:0007399 IDA
    spinal cord motor neuron differentiation GO:0021522 ISS
    neuromuscular junction development GO:0007528 ISS
Subcellular Localization
    postsynaptic membrane GO:0045211 IDA
    nucleus GO:0005634 IDA
    cell junction GO:0030054 IEA
    cytoplasm GO:0005737 IDA
 Experiment description of studies that identified ZC4H2 in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ZC4H2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 MGC2749  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which ZC4H2 is involved
No pathways found





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