Gene description for SLC25A31
Gene name solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
Gene symbol SLC25A31
Other names/aliases AAC4
ANT4
SFEC35kDa
Species Homo sapiens
 Database cross references - SLC25A31
ExoCarta ExoCarta_83447
Entrez Gene 83447
HGNC 25319
MIM 610796
UniProt Q9H0C2  
 SLC25A31 identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells 25944692    
Thymus 23844026    
 Gene ontology annotations for SLC25A31
Molecular Function
    transporter activity GO:0005215 IEA
Biological Process
    transmembrane transport GO:0055085 IEA
Subcellular Localization
    mitochondrion GO:0005739 IDA
    motile cilium GO:0031514 IEA
    integral component of membrane GO:0016021 IEA
    mitochondrial inner membrane GO:0005743 IEA
    nucleus GO:0005634 IDA
 Experiment description of studies that identified SLC25A31 in exosomes
1
Experiment ID 224
ISEV standards
EM|AFM
EV Biophysical techniques
Alix|TSG101
EV Cytosolic markers
CD63|CD81
EV Membrane markers
GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
2
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SLC25A31
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which SLC25A31 is involved
No pathways found





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