Gene description for SMARCD2
Gene name SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
Gene symbol SMARCD2
Other names/aliases BAF60B
CRACD2
PRO2451
Rsc6p
Species Homo sapiens
 Database cross references - SMARCD2
ExoCarta ExoCarta_6603
Entrez Gene 6603
HGNC 11107
MIM 601736
UniProt Q92925  
 SMARCD2 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for SMARCD2
Molecular Function
    protein binding GO:0005515 IPI
    nucleosomal DNA binding GO:0031492 IDA
    RNA polymerase II distal enhancer sequence-specific DNA binding GO:0000980 IDA
    transcription coactivator activity GO:0003713 NAS
    RNA polymerase II core promoter proximal region sequence-specific DNA binding GO:0000978 IDA
Biological Process
    transcription, DNA-templated GO:0006351 IEA
    chromatin remodeling GO:0006338 IDA
    nucleosome disassembly GO:0006337 IDA
    regulation of transcription from RNA polymerase II promoter GO:0006357 NAS
    ATP-dependent chromatin remodeling GO:0043044 IDA
Subcellular Localization
    nuclear chromatin GO:0000790 IDA
    nucleus GO:0005634 IDA
    SWI/SNF complex GO:0016514 IDA
    protein complex GO:0043234 IDA
 Experiment description of studies that identified SMARCD2 in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SMARCD2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 BRCA1 672
Co-purification Homo sapiens
2 XRN1 54464
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which SMARCD2 is involved
PathwayEvidenceSource
RMTs methylate histone arginines TAS Reactome





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