Experiment description of studies that identified BPTF in sEVs

1 Experiment ID 237 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocytes Sample name MIHA Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RNA Sequencing

Protein-protein interactions for BPTF

Protein Interactor ExoCarta ID Identification method PubMed Species 1 SLFN11 91607 Affinity Capture-MS Homo sapiens 2 HIST2H2BE 8349 Affinity Capture-MS Homo sapiens 3 GATAD2B 57459 Affinity Capture-MS Homo sapiens 4 HSPB7   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 5 KPNA3 3839 Co-fractionation Homo sapiens 6 HDAC2 3066 Affinity Capture-MS Homo sapiens 7 ELF1 1997 Proximity Label-MS Homo sapiens 8 MAGEA3   Affinity Capture-MS Homo sapiens 9 KPNA1 3836 Affinity Capture-MS Homo sapiens 10 BUB1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 11 ZNF296   Affinity Capture-MS Homo sapiens 12 H3.1   Reconstituted Complex Bos taurus 13 TPX2   Affinity Capture-MS Homo sapiens 14 HIST1H2BG 8339 Proximity Label-MS Homo sapiens 15 RPS19 6223 Co-fractionation Homo sapiens 16 BRD2   Affinity Capture-MS Homo sapiens 17 PGR   Affinity Capture-Western Homo sapiens 18 SAP30 8819 Affinity Capture-MS Homo sapiens 19 ETS1   Proximity Label-MS Homo sapiens 20 SMARCD2 6603 Co-fractionation Homo sapiens 21 ELF4 2000 Proximity Label-MS Homo sapiens 22 CENPA   Proximity Label-MS Homo sapiens 23 APEX1 328 Proximity Label-MS Homo sapiens 24 KIAA1429 25962 Co-fractionation Homo sapiens 25 PPP1R12A 4659 Co-fractionation Homo sapiens 26 NCOR1   Co-fractionation Homo sapiens 27 MTF2   Affinity Capture-MS Homo sapiens 28 CHAF1A   Affinity Capture-MS Homo sapiens 29 KLF8   Proximity Label-MS Homo sapiens 30 PDIA6 10130 Cross-Linking-MS (XL-MS) Homo sapiens 31 RFXANK   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 32 SMARCA1 6594 Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens 33 CDK2AP1   Affinity Capture-MS Homo sapiens 34 EIF3B 8662 Cross-Linking-MS (XL-MS) Homo sapiens 35 ARID4B   Affinity Capture-MS Homo sapiens 36 ZNF512B   Affinity Capture-MS Homo sapiens 37 POU5F1   Affinity Capture-MS Homo sapiens 38 SIN3B   Affinity Capture-MS Homo sapiens 39 KRT78 196374 Affinity Capture-MS Homo sapiens 40 EED   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 41 ZNF219   Affinity Capture-MS Homo sapiens 42 PHF1   Affinity Capture-MS Homo sapiens 43 CHD3 1107 Affinity Capture-MS Homo sapiens 44 MAD2L1 4085 Affinity Capture-MS Homo sapiens 45 MTA2 9219 Affinity Capture-MS Homo sapiens 46 BCL11B   Affinity Capture-MS Homo sapiens 47 H2AFZ 3015 Affinity Capture-MS Homo sapiens 48 RBBP7 5931 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens 49 SHPRH   Affinity Capture-MS Homo sapiens 50 HIST1H4A 8359 Affinity Capture-MS Homo sapiens 51 C17orf49 124944 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 52 TEAD1   Proximity Label-MS Homo sapiens 53 NFIX 4784 Proximity Label-MS Homo sapiens 54 IFI27L1   Affinity Capture-MS Homo sapiens 55 SNRNP200 23020 Co-fractionation Homo sapiens 56 LIN52   Affinity Capture-MS Homo sapiens 57 DEK 7913 Co-fractionation Homo sapiens 58 TRIM21 6737 Affinity Capture-MS Homo sapiens 59 FOXK2   Affinity Capture-MS Homo sapiens 60 SMAD3 4088 Reconstituted Complex Homo sapiens 61 RAD18   Affinity Capture-MS Homo sapiens 62 SUZ12   Affinity Capture-MS Homo sapiens 63 MYBL2 4605 Affinity Capture-MS Homo sapiens 64 SMAD2 4087 Reconstituted Complex Homo sapiens 65 HJURP   Affinity Capture-MS Homo sapiens 66 BRMS1L   Affinity Capture-MS Homo sapiens 67 SMC1A 8243 Affinity Capture-MS Homo sapiens 68 ZNF784   Affinity Capture-MS Homo sapiens 69 WHSC1L1   Affinity Capture-MS Homo sapiens 70 HECTD1 25831 Affinity Capture-MS Homo sapiens 71 SUDS3   Affinity Capture-MS Homo sapiens 72 MRPL22   Affinity Capture-MS Homo sapiens 73 PHF12   Affinity Capture-MS Homo sapiens 74 C3orf49   Affinity Capture-MS Homo sapiens 75 CEBPA   Proximity Label-MS Homo sapiens 76 CD3EAP   Proximity Label-MS Homo sapiens 77 TPR 7175 Co-fractionation Homo sapiens 78 BCL11A 53335 Affinity Capture-MS Homo sapiens 79 PAX6   Proximity Label-MS Homo sapiens 80 MAZ 4150 Reconstituted Complex Homo sapiens Two-hybrid Homo sapiens Reconstituted Complex Homo sapiens Two-hybrid Homo sapiens 81 HIST1H3A 8350 Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens Proximity Label-MS Homo sapiens Affinity Capture-Western Homo sapiens 82 NUP62CL   Affinity Capture-MS Homo sapiens 83 BAG2 9532 Affinity Capture-MS Homo sapiens 84 SMARCA5 8467 Affinity Capture-MS Homo sapiens Co-fractionation Homo sapiens Affinity Capture-MS Homo sapiens 85 SIRT7   Affinity Capture-MS Homo sapiens 86 NCAPH2   Affinity Capture-MS Homo sapiens 87 TFAP4 7023 Co-fractionation Homo sapiens 88 DCAF13 25879 Affinity Capture-MS Homo sapiens 89 MECP2 4204 Affinity Capture-MS Homo sapiens 90 EGFR 1956 Affinity Capture-MS Homo sapiens Negative Genetic Homo sapiens 91 YY1 7528 Proximity Label-MS Homo sapiens 92 RBBP4 5928 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens 93 HIST3H3 8290 Reconstituted Complex Homo sapiens Protein-peptide Homo sapiens 94 HNF4A   Proximity Label-MS Homo sapiens 95 LIN9   Affinity Capture-MS Homo sapiens 96 RPA3 6119 Proximity Label-MS Homo sapiens 97 DLST 1743 Affinity Capture-MS Homo sapiens 98 MBD2 8932 Affinity Capture-MS Homo sapiens 99 HNF1B   Proximity Label-MS Homo sapiens 100 Junb   Affinity Capture-MS Mus musculus 101 BANF1 8815 Cross-Linking-MS (XL-MS) Homo sapiens 102 ARID1A 8289 Negative Genetic Homo sapiens 103 HIST1H4I 8294 Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens Protein-peptide Homo sapiens Reconstituted Complex Homo sapiens Co-crystal Structure Homo sapiens 104 HAT1 8520 Affinity Capture-MS Homo sapiens 105 CHD5 26038 Affinity Capture-MS Homo sapiens 106 BRD3 8019 Affinity Capture-MS Homo sapiens 107 IL1A   Affinity Capture-MS Homo sapiens 108 GATAD2A 54815 Affinity Capture-MS Homo sapiens 109 LLGL2 3993 Affinity Capture-MS Homo sapiens 110 PLEKHA4 57664 Affinity Capture-MS Homo sapiens 111 PARP1 142 Affinity Capture-MS Homo sapiens 112 MYOD1   Proximity Label-MS Homo sapiens 113 SIN3A   Affinity Capture-MS Homo sapiens 114 TP53 7157 Affinity Capture-MS Homo sapiens Negative Genetic Homo sapiens 115 SAP130   Affinity Capture-MS Homo sapiens 116 MBD3 53615 Affinity Capture-MS Homo sapiens 117 MTA1 9112 Affinity Capture-MS Homo sapiens 118 Dync1li1 235661 Affinity Capture-MS Mus musculus 119 CALU 813 Co-fractionation Homo sapiens 120 KEAP1 9817 Negative Genetic Homo sapiens Two-hybrid Homo sapiens Reconstituted Complex Homo sapiens Co-localization Homo sapiens 121 DPY30 84661 Affinity Capture-MS Homo sapiens 122 SQSTM1 8878 Two-hybrid Homo sapiens 123 PBRM1 55193 Negative Genetic Homo sapiens 124 HDAC1 3065 Affinity Capture-MS Homo sapiens 125 CHD4 1108 Affinity Capture-MS Homo sapiens 126 EPB41L2 2037 Co-fractionation Homo sapiens 127 HMGXB4 10042 Affinity Capture-MS Homo sapiens Co-fractionation Homo sapiens 128 EZH2   Affinity Capture-MS Homo sapiens 129 H3F3A 3020 Reconstituted Complex Homo sapiens Co-crystal Structure Homo sapiens 130 C1QBP 708 Cross-Linking-MS (XL-MS) Homo sapiens 131 MTA3 57504 Affinity Capture-MS Homo sapiens 132 ELF2   Proximity Label-MS Homo sapiens 133 CUL7 9820 Affinity Capture-MS Homo sapiens 134 GATAD1   Affinity Capture-MS Homo sapiens 135 USF1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 136 CHAF1B   Affinity Capture-MS Homo sapiens 137 PWWP2A   Affinity Capture-MS Homo sapiens 138 MEN1 4221 Affinity Capture-MS Homo sapiens 139 LIN37   Affinity Capture-MS Homo sapiens 140 TIMM13 26517 Affinity Capture-MS Homo sapiens 141 NHLH1   Proximity Label-MS Homo sapiens View the network

Pathways in which BPTF is involved

No pathways found