Experiment description of studies that identified HMGXB4 in sEVs

1 Experiment ID 834 MISEV standards ✔ EM Biophysical techniques ✔ LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P" Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

2 Experiment ID 835 MISEV standards ✔ EM Biophysical techniques ✔ CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P" Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

Protein-protein interactions for HMGXB4

Protein Interactor ExoCarta ID Identification method PubMed Species 1 HIST2H2BE 8349 Affinity Capture-MS Homo sapiens 2 GATAD2B 57459 Affinity Capture-MS Homo sapiens 3 MAGEA3   Affinity Capture-MS Homo sapiens 4 KPNA1 3836 Affinity Capture-MS Homo sapiens 5 ZNF296   Affinity Capture-MS Homo sapiens 6 Nfyc 18046 Affinity Capture-MS Mus musculus 7 HIST1H2BG 8339 Proximity Label-MS Homo sapiens 8 SMARCE1 6605 Co-fractionation Homo sapiens 9 BRD2   Affinity Capture-MS Homo sapiens 10 SAP30 8819 Affinity Capture-MS Homo sapiens 11 RABGAP1L 9910 Affinity Capture-MS Homo sapiens 12 CENPA   Proximity Label-MS Homo sapiens 13 NCOR1   Co-fractionation Homo sapiens 14 MTF2   Affinity Capture-MS Homo sapiens 15 KIF22   Affinity Capture-MS Homo sapiens 16 CHAF1A   Affinity Capture-MS Homo sapiens 17 SMARCA1 6594 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 18 CDK2AP1   Affinity Capture-MS Homo sapiens 19 ARID4B   Affinity Capture-MS Homo sapiens 20 ZNF512B   Affinity Capture-MS Homo sapiens 21 SIN3B   Affinity Capture-MS Homo sapiens 22 NR1H2   Two-hybrid Homo sapiens 23 RAD51   Affinity Capture-MS Homo sapiens 24 EED   Affinity Capture-MS Homo sapiens 25 ZNF219   Affinity Capture-MS Homo sapiens 26 PHF1   Affinity Capture-MS Homo sapiens 27 MYCN   Affinity Capture-MS Homo sapiens 28 CHD3 1107 Affinity Capture-MS Homo sapiens 29 MTA2 9219 Affinity Capture-MS Homo sapiens 30 HAT1 8520 Affinity Capture-MS Homo sapiens 31 H2AFZ 3015 Affinity Capture-MS Homo sapiens 32 JMJD6 23210 Two-hybrid Homo sapiens 33 SHPRH   Affinity Capture-MS Homo sapiens 34 HIST1H4A 8359 Affinity Capture-MS Homo sapiens 35 Rock1   Affinity Capture-MS Mus musculus 36 C17orf49 124944 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 37 CBX3 11335 Proximity Label-MS Homo sapiens 38 LIN52   Affinity Capture-MS Homo sapiens 39 FOXK2   Affinity Capture-MS Homo sapiens 40 BPTF 2186 Co-fractionation Homo sapiens Affinity Capture-MS Homo sapiens 41 SYNCRIP 10492 Affinity Capture-MS Homo sapiens 42 BRMS1L   Affinity Capture-MS Homo sapiens 43 MYBL2 4605 Affinity Capture-MS Homo sapiens 44 HJURP   Affinity Capture-MS Homo sapiens 45 PML 5371 Affinity Capture-MS Homo sapiens 46 SUDS3   Affinity Capture-MS Homo sapiens 47 PHF12   Affinity Capture-MS Homo sapiens 48 Cep131   Affinity Capture-MS Mus musculus 49 BCL11A 53335 Affinity Capture-MS Homo sapiens 50 HABP4   Two-hybrid Homo sapiens 51 SMARCA5 8467 Affinity Capture-MS Homo sapiens Co-fractionation Homo sapiens Affinity Capture-MS Homo sapiens 52 MX1 4599 Two-hybrid Homo sapiens 53 MECP2 4204 Affinity Capture-MS Homo sapiens 54 YY1 7528 Proximity Label-MS Homo sapiens 55 SUZ12   Affinity Capture-MS Homo sapiens 56 HIST3H3 8290 Protein-peptide Homo sapiens 57 RRAS 6237 Affinity Capture-MS Homo sapiens 58 LIN9   Affinity Capture-MS Homo sapiens 59 DNAJC24   Affinity Capture-MS Homo sapiens 60 EPM2A   Two-hybrid Homo sapiens 61 Tpx2   Affinity Capture-MS Mus musculus 62 CNTROB   Affinity Capture-MS Homo sapiens 63 MBD2 8932 Affinity Capture-MS Homo sapiens 64 TBCA 6902 Affinity Capture-MS Homo sapiens 65 Mad2l1 56150 Affinity Capture-MS Mus musculus 66 CHD5 26038 Affinity Capture-MS Homo sapiens 67 BRD3 8019 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 68 RBBP4 5928 Affinity Capture-MS Homo sapiens Co-fractionation Homo sapiens Affinity Capture-MS Homo sapiens 69 ARAP1 116985 Affinity Capture-MS Homo sapiens 70 TNNT1   Two-hybrid Homo sapiens 71 UROD 7389 Two-hybrid Homo sapiens 72 GATAD2A 54815 Affinity Capture-MS Homo sapiens 73 LLGL2 3993 Affinity Capture-MS Homo sapiens 74 SAP130   Affinity Capture-MS Homo sapiens 75 SIN3A   Affinity Capture-MS Homo sapiens 76 MBD3 53615 Affinity Capture-MS Homo sapiens 77 MTA1 9112 Affinity Capture-MS Homo sapiens 78 CHD4 1108 Affinity Capture-MS Homo sapiens 79 KIFAP3 22920 Affinity Capture-MS Homo sapiens 80 TSC22D1 8848 Two-hybrid Homo sapiens 81 EZH2   Affinity Capture-MS Homo sapiens 82 MTA3 57504 Affinity Capture-MS Homo sapiens 83 GATAD1   Affinity Capture-MS Homo sapiens 84 CHAF1B   Affinity Capture-MS Homo sapiens 85 PWWP2A   Affinity Capture-MS Homo sapiens 86 SSRP1 6749 Affinity Capture-MS Homo sapiens 87 LIN37   Affinity Capture-MS Homo sapiens View the network

Pathways in which HMGXB4 is involved

No pathways found