Gene description for MTA3
Gene name metastasis associated 1 family, member 3
Gene symbol MTA3
Other names/aliases -
Species Homo sapiens
 Database cross references - MTA3
ExoCarta ExoCarta_57504
Entrez Gene 57504
HGNC 23784
MIM 609050
UniProt Q9BTC8  
 MTA3 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for MTA3
Molecular Function
    sequence-specific DNA binding transcription factor activity GO:0003700 IEA
    protein binding GO:0005515 IPI
    zinc ion binding GO:0008270 IEA
    chromatin binding GO:0003682 IEA
    sequence-specific DNA binding GO:0043565 IEA
Biological Process
    chromatin organization GO:0006325 TAS
    negative regulation of transcription, DNA-templated GO:0045892 IMP
Subcellular Localization
    nucleoplasm GO:0005654 TAS
    nucleus GO:0005634 IDA
    intracellular membrane-bounded organelle GO:0043231 IDA
 Experiment description of studies that identified MTA3 in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for MTA3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which MTA3 is involved
PathwayEvidenceSource
HDACs deacetylate histones TAS Reactome
RNA Polymerase I Transcription Initiation TAS Reactome





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