Experiment description of studies that identified FAM219A in exosomes

1 Experiment ID 834 MISEV standards ✔ EM Biophysical techniques ✔ LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P" Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

2 Experiment ID 835 MISEV standards ✔ EM Biophysical techniques ✔ CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P" Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

Protein-protein interactions for FAM219A

Protein Interactor ExoCarta ID Identification method PubMed Species 1 GATAD2A 54815 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 2 NIPSNAP3A   Two-hybrid Homo sapiens 3 HNRNPH1 3187 Affinity Capture-RNA Homo sapiens 4 SHPK 23729 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 5 BTRC 8945 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 6 FBXW11   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 7 RAD50 10111 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 8 KLHL24   Affinity Capture-MS Homo sapiens 9 CHRNA4   Affinity Capture-MS Homo sapiens 10 MTA2 9219 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 11 LAMTOR1 55004 Proximity Label-MS Homo sapiens 12 METTL7A 25840 Proximity Label-MS Homo sapiens 13 RAB5A 5868 Proximity Label-MS Homo sapiens 14 FBXO10   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 15 MTA1 9112 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 16 FBXO21   Affinity Capture-MS Homo sapiens 17 LIMS3 96626 Two-hybrid Homo sapiens 18 MRE11A 4361 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 19 ATE1 11101 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 20 CTU2 348180 Affinity Capture-MS Homo sapiens 21 UBR3   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 22 RABGGTB 5876 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 23 CSNK1G1 53944 Two-hybrid Homo sapiens 24 PDE6D 5147 Affinity Capture-MS Homo sapiens Two-hybrid Homo sapiens 25 GORASP1 64689 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 26 POLA2   Two-hybrid Homo sapiens 27 KCNE3   Affinity Capture-MS Homo sapiens 28 B3GAT1   Proximity Label-MS Homo sapiens 29 GATAD2B 57459 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 30 MARS2 92935 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 31 C16orf58 64755 Affinity Capture-MS Homo sapiens 32 NBN 4683 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 33 HIST1H1A 3024 Affinity Capture-MS Homo sapiens 34 MTA3 57504 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 35 KRAS 3845 Proximity Label-MS Homo sapiens 36 LIMS3L 100288695 Two-hybrid Homo sapiens 37 GPR37   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 38 OBSL1 23363 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 39 MBD3 53615 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 40 SPRY2 10253 Two-hybrid Homo sapiens 41 CAV1 857 Proximity Label-MS Homo sapiens 42 ELOVL5 60481 Proximity Label-MS Homo sapiens 43 WDFY1 57590 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens View the network

Pathways in which FAM219A is involved

No pathways found