Gene ontology annotations for SHPK
Experiment description of studies that identified SHPK in exosomes
1
Experiment ID
237
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule
mRNA
Identification method
RNA Sequencing
PubMed ID
26054723
Organism
Homo sapiens
Experiment description
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors
"He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name
Carcinogenesis
Publication year
2015
Sample
Hepatocytes
Sample name
MIHA
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.13-1.19 g/mL
Molecules identified in the study
Protein RNA
Methods used in the study
Western blotting Mass spectrometry RNA Sequencing
2
Experiment ID
488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Homo sapiens
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Mesenchymal stem cells
Sample name
UCMSC
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
3
Experiment ID
211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
"Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
IGROV1
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
4
Experiment ID
212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
"Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
OVCAR-3
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
Protein-protein interactions for SHPK
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
LRRC8E
80131
Affinity Capture-MS
Homo sapiens
2
NR2F2
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
3
SERBP1
26135
Affinity Capture-MS
Homo sapiens
4
NFATC1
4772
Affinity Capture-MS
Homo sapiens
5
FAM126A
84668
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
6
BTBD9
Affinity Capture-MS
Homo sapiens
7
MCOLN2
Affinity Capture-MS
Homo sapiens
8
FAM219A
203259
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
9
ARFGAP3
26286
Affinity Capture-MS
Homo sapiens
10
LRP4
4038
Affinity Capture-MS
Homo sapiens
11
C10orf88
Affinity Capture-MS
Homo sapiens
12
RAB6B
51560
Affinity Capture-MS
Homo sapiens
13
THYN1
29087
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
14
TCF25
22980
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
15
PDDC1
347862
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
16
PSMF1
9491
Affinity Capture-MS
Homo sapiens
17
MDM2
Two-hybrid
Homo sapiens
18
LINC01587
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
19
C10orf55
Affinity Capture-MS
Homo sapiens
20
EID2B
Affinity Capture-MS
Homo sapiens
21
TRAF3
7187
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
View the network
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Pathways in which SHPK is involved