Gene description for LRP4
Gene name	low density lipoprotein receptor-related protein 4
Gene symbol	LRP4
Other names/aliases	CLSS CMS17 LRP-4 LRP10 MEGF7 SOST2
Species	Homo sapiens
Database cross references - LRP4
ExoCarta	ExoCarta_4038
Entrez Gene	4038
HGNC	6696
MIM	604270
UniProt	O75096
LRP4 identified in exosomes derived from the following tissue/cell type
Colorectal cancer cells	19837982

Gene ontology annotations for LRP4

Molecular Function     apolipoprotein binding GO:0034185 IEA     protein homodimerization activity GO:0042803 IEA     calcium ion binding GO:0005509 IEA     Wnt-activated receptor activity GO:0042813 IBA     Wnt-protein binding GO:0017147 IBA     scaffold protein binding GO:0097110 ISS     protein binding GO:0005515 IPI     receptor tyrosine kinase binding GO:0030971 ISS Biological Process     skeletal muscle acetylcholine-gated channel clustering GO:0071340 ISS     extracellular matrix organization GO:0030198 TAS     protein heterotetramerization GO:0051290 ISS     BMP signaling pathway GO:0030509 IEA     odontogenesis of dentin-containing tooth GO:0042475 IEA     canonical Wnt signaling pathway GO:0060070 IBA     Wnt signaling pathway involved in dorsal/ventral axis specification GO:0044332 IBA     regulation of protein phosphorylation GO:0001932 IEA     proximal/distal pattern formation GO:0009954 IEA     endocytosis GO:0006897 IEA     presynaptic membrane assembly GO:0097105 ISS     limb development GO:0060173 IDA     negative regulation of axonogenesis GO:0050771 ISS     negative regulation of canonical Wnt signaling pathway GO:0090090 IMP     synaptic growth at neuromuscular junction GO:0051124 ISS     negative regulation of ossification GO:0030279 IMP     embryonic digit morphogenesis GO:0042733 IEA     kidney development GO:0001822 IDA     synapse organization GO:0050808 ISS     positive regulation of presynaptic membrane organization GO:1901631 ISS     postsynaptic membrane assembly GO:0097104 ISS     dendrite morphogenesis GO:0048813 ISS     hair follicle development GO:0001942 IEA Subcellular Localization     integral component of membrane GO:0016021 IEA     neuronal cell body GO:0043025 ISS     neuromuscular junction GO:0031594 ISS     postsynaptic density GO:0014069 ISS     cell surface GO:0009986 ISS     synaptic membrane GO:0097060 ISS     flotillin complex GO:0016600 ISS     dendrite GO:0030425 ISS