Gene description for LIMS3L
Gene name LIM and senescent cell antigen-like domains 3-like
Gene symbol LIMS3L
Other names/aliases -
Species Homo sapiens
 Database cross references - LIMS3L
ExoCarta ExoCarta_100288695
Vesiclepedia VP_100288695
Entrez Gene 100288695
HGNC 39941
UniProt P0CW20   P0CW19  
 LIMS3L identified in sEVs derived from the following tissue/cell type
Neuroblastoma cells 25944692    
 Gene ontology annotations for LIMS3L
Molecular Function
    protein binding GO:0005515 IPI
    metal ion binding GO:0046872 IEA
Subcellular Localization
    focal adhesion GO:0005925 IEA
 Experiment description of studies that identified LIMS3L in sEVs
1
Experiment ID 224
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for LIMS3L
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 BTF3 689
Affinity Capture-MS Homo sapiens
2 CRX  
Two-hybrid Homo sapiens
3 BCL6  
Two-hybrid Homo sapiens
4 FAM219A 203259
Two-hybrid Homo sapiens
5 TRIM49C  
Two-hybrid Homo sapiens
6 KRTAP11-1  
Two-hybrid Homo sapiens
7 C10orf55  
Two-hybrid Homo sapiens
8 RUSC1  
Two-hybrid Homo sapiens
9 ARID5A  
Two-hybrid Homo sapiens
10 KLHDC7B  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which LIMS3L is involved
No pathways found





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