Experiment description of studies that identified SOX5 in exosomes

1 Experiment ID 237 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocytes Sample name MIHA Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RNA Sequencing

Protein-protein interactions for SOX5

Protein Interactor ExoCarta ID Identification method PubMed Species 1 KLHL9 55958 Affinity Capture-MS Homo sapiens 2 MORN3   Two-hybrid Homo sapiens 3 IGF2BP1 10642 Affinity Capture-MS Homo sapiens 4 ATF7IP 55729 Proximity Label-MS Homo sapiens 5 UQCRFS1 7386 Two-hybrid Homo sapiens 6 KLF8   Proximity Label-MS Homo sapiens 7 ZFHX4   Proximity Label-MS Homo sapiens 8 FEV   Proximity Label-MS Homo sapiens 9 NFIB   Proximity Label-MS Homo sapiens 10 KIFC3 3801 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 11 AES 166 Two-hybrid Homo sapiens Two-hybrid Homo sapiens Proximity Label-MS Homo sapiens 12 POGZ 23126 Proximity Label-MS Homo sapiens 13 TEX11   Two-hybrid Homo sapiens 14 DBN1 1627 Affinity Capture-MS Homo sapiens 15 XRN2 22803 Affinity Capture-MS Homo sapiens 16 SOX2   Affinity Capture-MS Homo sapiens 17 APP 351 Reconstituted Complex Homo sapiens 18 TPM4 7171 Affinity Capture-MS Homo sapiens 19 SATB2   Proximity Label-MS Homo sapiens 20 CAPRIN1 4076 Affinity Capture-MS Homo sapiens 21 LMO2   Two-hybrid Homo sapiens 22 NCOR1   Proximity Label-MS Homo sapiens 23 POLDIP3 84271 Affinity Capture-MS Homo sapiens 24 MRPS34 65993 Affinity Capture-MS Homo sapiens 25 TFAM 7019 Proximity Label-MS Homo sapiens Affinity Capture-MS Homo sapiens 26 GSE1 23199 Proximity Label-MS Homo sapiens 27 ZFHX3   Proximity Label-MS Homo sapiens 28 ARID4B   Proximity Label-MS Homo sapiens 29 CUX1 1523 Proximity Label-MS Homo sapiens 30 KMT2D 8085 Proximity Label-MS Homo sapiens 31 NCOR2   Proximity Label-MS Homo sapiens 32 MED27   Two-hybrid Homo sapiens 33 EWSR1 2130 Affinity Capture-MS Homo sapiens 34 BCOR   Proximity Label-MS Homo sapiens 35 HMG20B   Proximity Label-MS Homo sapiens 36 ARID5A   Two-hybrid Homo sapiens Two-hybrid Homo sapiens 37 SSBP1 6742 Proximity Label-MS Homo sapiens Affinity Capture-MS Homo sapiens 38 SMAD5 4090 Two-hybrid Homo sapiens 39 CHD3 1107 Proximity Label-MS Homo sapiens 40 SOX5 6660 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 41 RCOR3   Proximity Label-MS Homo sapiens 42 KIF14 9928 Affinity Capture-MS Homo sapiens 43 PRR20A   Two-hybrid Homo sapiens 44 FOXP1 27086 Proximity Label-MS Homo sapiens 45 ILF2 3608 Affinity Capture-MS Homo sapiens 46 KLF16   Proximity Label-MS Homo sapiens 47 ZHX1   Proximity Label-MS Homo sapiens 48 S100A2 6273 Affinity Capture-MS Homo sapiens 49 FOXC1   Proximity Label-MS Homo sapiens 50 HMG20A   Proximity Label-MS Homo sapiens 51 RPS17 6218 Affinity Capture-MS Homo sapiens 52 ANKRD40 91369 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 53 CDC23 8697 Two-hybrid Homo sapiens 54 RBM28 55131 Proximity Label-MS Homo sapiens 55 CCAR2 57805 Affinity Capture-MS Homo sapiens 56 IRF2BPL 64207 Proximity Label-MS Homo sapiens 57 MSX2   Two-hybrid Homo sapiens 58 TBR1   Proximity Label-MS Homo sapiens 59 NFIX 4784 Reconstituted Complex Homo sapiens 60 TRIM24   Proximity Label-MS Homo sapiens 61 ZHX3   Proximity Label-MS Homo sapiens 62 CPVL 54504 Proximity Label-MS Homo sapiens Affinity Capture-MS Homo sapiens 63 UBE2I 7329 Two-hybrid Homo sapiens 64 PPIL2   Proximity Label-MS Homo sapiens 65 NFIA 4774 Proximity Label-MS Homo sapiens 66 ZHX2   Proximity Label-MS Homo sapiens 67 FLOT1 10211 Affinity Capture-MS Homo sapiens 68 DCAF7 10238 Proximity Label-MS Homo sapiens 69 LHX3   Proximity Label-MS Homo sapiens 70 MBD2 8932 Proximity Label-MS Homo sapiens 71 CIC 23152 Proximity Label-MS Homo sapiens 72 PABPN1 8106 Affinity Capture-MS Homo sapiens 73 ZNF581   Two-hybrid Homo sapiens 74 CHD7   Proximity Label-MS Homo sapiens 75 ZNF608   Proximity Label-MS Homo sapiens 76 SOX1 6656 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 77 FLOT2 2319 Affinity Capture-MS Homo sapiens 78 ZNF609   Proximity Label-MS Homo sapiens 79 ZMYM4   Proximity Label-MS Homo sapiens 80 SOX7   Proximity Label-MS Homo sapiens 81 PAX6   Proximity Label-MS Homo sapiens 82 SMCHD1 23347 Proximity Label-MS Homo sapiens 83 MRPS12   Affinity Capture-MS Homo sapiens 84 RPS2 6187 Two-hybrid Homo sapiens 85 SOX6   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 86 TCF20   Proximity Label-MS Homo sapiens 87 SEC13 6396 Affinity Capture-MS Homo sapiens 88 FAM46B   Two-hybrid Homo sapiens 89 ACAD11 84129 Affinity Capture-MS Homo sapiens 90 DACH1   Proximity Label-MS Homo sapiens 91 FTH1 2495 Two-hybrid Homo sapiens 92 RBM33   Affinity Capture-MS Homo sapiens 93 BRMS1L   Proximity Label-MS Homo sapiens 94 LARS 51520 Affinity Capture-MS Homo sapiens 95 CRX   Two-hybrid Homo sapiens Two-hybrid Homo sapiens 96 SMAD1 4086 Two-hybrid Homo sapiens 97 L3MBTL3   Proximity Label-MS Homo sapiens 98 ZNF521   Proximity Label-MS Homo sapiens 99 RPS13 6207 Affinity Capture-MS Homo sapiens 100 PROSER1   Proximity Label-MS Homo sapiens 101 MSANTD2   Proximity Label-MS Homo sapiens 102 SOX11   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 103 KAT5   Two-hybrid Homo sapiens 104 TBL1X 6907 Proximity Label-MS Homo sapiens 105 TTC1 7265 Two-hybrid Homo sapiens 106 PCGF1 84759 Proximity Label-MS Homo sapiens 107 RPS11 6205 Affinity Capture-MS Homo sapiens 108 SUMO1P1   Two-hybrid Homo sapiens 109 PYGO2   Proximity Label-MS Homo sapiens 110 FOXP4   Proximity Label-MS Homo sapiens 111 FOXK1 221937 Proximity Label-MS Homo sapiens 112 KDM2B 84678 Proximity Label-MS Homo sapiens 113 TRPS1   Proximity Label-MS Homo sapiens 114 SATB1 6304 Proximity Label-MS Homo sapiens 115 GATAD2A 54815 Proximity Label-MS Homo sapiens 116 CDC25A   Two-hybrid Homo sapiens 117 TAF6 6878 Affinity Capture-MS Homo sapiens 118 PHB2 11331 Affinity Capture-MS Homo sapiens 119 PRRC2A 7916 Affinity Capture-MS Homo sapiens 120 TRAF2 7186 Two-hybrid Homo sapiens 121 TSHZ3   Proximity Label-MS Homo sapiens 122 SMAD7   Two-hybrid Homo sapiens 123 SAP130   Proximity Label-MS Homo sapiens 124 RGPD8   Affinity Capture-MS Homo sapiens 125 ATXN1L   Proximity Label-MS Homo sapiens 126 PRRC2C 23215 Affinity Capture-MS Homo sapiens 127 LSM14A 26065 Affinity Capture-MS Homo sapiens 128 KLF3   Proximity Label-MS Homo sapiens 129 TLE1 7088 Proximity Label-MS Homo sapiens 130 ZBTB26   Two-hybrid Homo sapiens 131 G3BP1 10146 Affinity Capture-MS Homo sapiens 132 CHD6 84181 Proximity Label-MS Homo sapiens 133 QSER1   Proximity Label-MS Homo sapiens 134 CDK6 1021 Biochemical Activity Homo sapiens 135 ZNF7   Affinity Capture-MS Homo sapiens 136 PGAM2 5224 Affinity Capture-MS Homo sapiens 137 POU2F1 5451 Proximity Label-MS Homo sapiens 138 ATAD3A 55210 Affinity Capture-MS Homo sapiens 139 RPL39 6170 Affinity Capture-MS Homo sapiens 140 MAGED1 9500 Two-hybrid Homo sapiens 141 CBX8 57332 Two-hybrid Homo sapiens 142 LIN54   Proximity Label-MS Homo sapiens 143 ZNF503 84858 Proximity Label-MS Homo sapiens 144 MTA3 57504 Proximity Label-MS Homo sapiens 145 SOX13   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Proximity Label-MS Homo sapiens 146 HNF1B   Reconstituted Complex Homo sapiens 147 CEP85   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 148 NFIC 4782 Proximity Label-MS Homo sapiens Reconstituted Complex Homo sapiens 149 LMO1   Two-hybrid Homo sapiens Two-hybrid Homo sapiens 150 BIRC7   Two-hybrid Homo sapiens 151 VPS72   Proximity Label-MS Homo sapiens 152 SP7   Proximity Label-MS Homo sapiens 153 BCL7A   Proximity Label-MS Homo sapiens 154 RCOR1   Affinity Capture-MS Homo sapiens View the network

Pathways in which SOX5 is involved

No pathways found