Gene description for RPL39
Gene name ribosomal protein L39
Gene symbol RPL39
Other names/aliases L39
RPL39P42
RPL39_23_1806
Species Homo sapiens
 Database cross references - RPL39
ExoCarta ExoCarta_6170
Entrez Gene 6170
HGNC 10350
MIM 300899
UniProt P62891  
 RPL39 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for RPL39
Molecular Function
    structural constituent of ribosome GO:0003735 TAS
    RNA binding GO:0003723 TAS
Biological Process
    translational termination GO:0006415 TAS
    translational elongation GO:0006414 TAS
    translational initiation GO:0006413 TAS
    viral process GO:0016032 TAS
    cellular protein metabolic process GO:0044267 TAS
    gene expression GO:0010467 TAS
    SRP-dependent cotranslational protein targeting to membrane GO:0006614 TAS
    innate immune response in mucosa GO:0002227 IDA
    defense response to Gram-positive bacterium GO:0050830 IDA
    nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 TAS
    viral transcription GO:0019083 TAS
    viral life cycle GO:0019058 TAS
    antibacterial humoral response GO:0019731 IDA
    translation GO:0006412 TAS
Subcellular Localization
    cytosolic large ribosomal subunit GO:0022625 TAS
    cytosol GO:0005829 TAS
    extracellular space GO:0005615 IDA
 Experiment description of studies that identified RPL39 in exosomes
1
Experiment ID 235
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
2
Experiment ID 236
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for RPL39
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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