Gene description for RPL3L
Gene name ribosomal protein L3-like
Gene symbol RPL3L
Other names/aliases -
Species Homo sapiens
 Database cross references - RPL3L
ExoCarta ExoCarta_6123
Vesiclepedia VP_6123
Entrez Gene 6123
HGNC 10351
UniProt Q92901  
 RPL3L identified in exosomes derived from the following tissue/cell type
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
 Gene ontology annotations for RPL3L
Molecular Function
    structural constituent of ribosome GO:0003735 NAS
    RNA binding GO:0003723 TAS
Biological Process
    SRP-dependent cotranslational protein targeting to membrane GO:0006614 TAS
    viral process GO:0016032 TAS
    translational termination GO:0006415 TAS
    gene expression GO:0010467 TAS
    nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 TAS
    viral transcription GO:0019083 TAS
    viral life cycle GO:0019058 TAS
    translational initiation GO:0006413 TAS
    cellular protein metabolic process GO:0044267 TAS
    translational elongation GO:0006414 TAS
    translation GO:0006412 TAS
Subcellular Localization
    membrane GO:0016020 IDA
    cytosolic large ribosomal subunit GO:0022625 IDA
    cytosol GO:0005829 TAS
    ribosome GO:0005840 TAS
 Experiment description of studies that identified RPL3L in exosomes
1
Experiment ID 834
MISEV standards
✔
EM
EV Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
EV Enriched markers
✔
CANX
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 835
MISEV standards
✔
EM
EV Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
EV Enriched markers
✔
CANX
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for RPL3L
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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