Gene description for ZNF503
Gene name zinc finger protein 503
Gene symbol ZNF503
Other names/aliases NOLZ-1
NOLZ1
Nlz2
Species Homo sapiens
 Database cross references - ZNF503
ExoCarta ExoCarta_84858
Vesiclepedia VP_84858
Entrez Gene 84858
HGNC 23589
MIM 613902
UniProt Q96F45  
 ZNF503 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for ZNF503
Molecular Function
    protein binding GO:0005515 IPI
    metal ion binding GO:0046872 IEA
Biological Process
    negative regulation of cell population proliferation GO:0008285 IDA
    negative regulation of gene expression GO:0010629 IDA
    negative regulation of DNA-templated transcription GO:0045892 IBA
    neural precursor cell proliferation GO:0061351 IEA
    G1 to G0 transition involved in cell differentiation GO:0070315 IDA
Subcellular Localization
    nucleus GO:0005634 IBA
 Experiment description of studies that identified ZNF503 in exosomes
1
Experiment ID 126
MISEV standards
Biophysical techniques
GAPDH
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for ZNF503
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TLX1  
Proximity Label-MS Homo sapiens
2 FOXH1  
Two-hybrid Homo sapiens
3 PAX6  
Proximity Label-MS Homo sapiens
4 SOX5 6660
Proximity Label-MS Homo sapiens
5 CEP170P1  
Affinity Capture-MS Homo sapiens
6 DCK 1633
Affinity Capture-MS Homo sapiens
7 FEV  
Proximity Label-MS Homo sapiens
8 KRTAP19-1  
Two-hybrid Homo sapiens
9 ARID5A  
Two-hybrid Homo sapiens
10 SOX6  
Proximity Label-MS Homo sapiens
11 BAG2 9532
Affinity Capture-MS Homo sapiens
12 AES 166
Two-hybrid Homo sapiens
13 HSPBP1 23640
Affinity Capture-MS Homo sapiens
14 GATA2  
Proximity Label-MS Homo sapiens
15 FOXI1  
Proximity Label-MS Homo sapiens
16 PRDM1  
Proximity Label-MS Homo sapiens
17 FAM46B  
Two-hybrid Homo sapiens
18 TLX3  
Proximity Label-MS Homo sapiens
19 CYP1A1  
Affinity Capture-MS Homo sapiens
20 KLC1 3831
Affinity Capture-MS Homo sapiens
21 FOXL1  
Proximity Label-MS Homo sapiens
22 CCNJL  
Affinity Capture-MS Homo sapiens
23 HOXA1 3198
Affinity Capture-MS Homo sapiens
24 ATN1  
Two-hybrid Homo sapiens
25 WIBG 84305
Co-fractionation Homo sapiens
26 KLF16  
Proximity Label-MS Homo sapiens
27 PAX7  
Proximity Label-MS Homo sapiens
28 BRCA2 675
Affinity Capture-MS Homo sapiens
29 KRTAP6-2  
Two-hybrid Homo sapiens
30 CGRRF1  
Affinity Capture-MS Homo sapiens
31 HSPA2 3306
Affinity Capture-MS Homo sapiens
32 DCAF7 10238
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
33 PROP1  
Two-hybrid Homo sapiens
34 NUP35 129401
Proximity Label-MS Homo sapiens
35 HSPA1A 3303
Affinity Capture-MS Homo sapiens
36 PAX9  
Proximity Label-MS Homo sapiens
37 TCEAL1  
Affinity Capture-MS Homo sapiens
38 DCAF15  
Affinity Capture-MS Homo sapiens
39 GCM1  
Proximity Label-MS Homo sapiens
40 Snrnp70 20637
Affinity Capture-MS Mus musculus
41 SP7  
Proximity Label-MS Homo sapiens
42 TBR1  
Proximity Label-MS Homo sapiens
43 CEBPA  
Proximity Label-MS Homo sapiens
44 KRTAP3-3  
Two-hybrid Homo sapiens
45 GATA3  
Proximity Label-MS Homo sapiens
View the network image/svg+xml
 Pathways in which ZNF503 is involved
No pathways found





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