Experiment description of studies that identified PCGF1 in exosomes

1 Experiment ID 235 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N Journal name Carcinogenesis Publication year 2015 Sample Hepatocellular carcinoma cells Sample name HKCI-8 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RT-PCR RNA Sequencing

Protein-protein interactions for PCGF1

Protein Interactor ExoCarta ID Identification method PubMed Species 1 GATA1   Proximity Label-MS Homo sapiens 2 CCAR1 55749 Affinity Capture-MS Homo sapiens 3 HIST2H2BE 8349 Affinity Capture-MS Homo sapiens 4 CRBN   Affinity Capture-MS Homo sapiens 5 PQBP1   Affinity Capture-MS Homo sapiens 6 PCGF5   Two-hybrid Homo sapiens Affinity Capture-MS Homo sapiens 7 HRG 3273 Affinity Capture-MS Homo sapiens 8 CLIP1 6249 Affinity Capture-MS Homo sapiens 9 TCEB1 6921 Affinity Capture-MS Homo sapiens 10 IRF4   Proximity Label-MS Homo sapiens 11 FEV   Proximity Label-MS Homo sapiens 12 NFIB   Proximity Label-MS Homo sapiens 13 MORC4   Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens 14 FAM9B   Affinity Capture-MS Homo sapiens 15 EN1   Proximity Label-MS Homo sapiens 16 FCHO1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Two-hybrid Homo sapiens 17 PAX2   Proximity Label-MS Homo sapiens 18 USP9X 8239 Affinity Capture-MS Homo sapiens 19 CSNK2A1 1457 Affinity Capture-MS Homo sapiens 20 DCAF7 10238 Affinity Capture-MS Homo sapiens 21 TRIM55   Two-hybrid Homo sapiens 22 FBRS 64319 Affinity Capture-MS Homo sapiens 23 SOX10   Proximity Label-MS Homo sapiens 24 SOX2   Proximity Label-MS Homo sapiens 25 PCGF2 7703 Affinity Capture-MS Homo sapiens 26 ATG13 9776 Affinity Capture-MS Homo sapiens 27 DPPA4   Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens Co-purification Homo sapiens 28 KLF8   Proximity Label-MS Homo sapiens 29 GPATCH8   Affinity Capture-MS Homo sapiens 30 GCM1   Proximity Label-MS Homo sapiens 31 KDM2A   Affinity Capture-MS Homo sapiens 32 E2F6 1876 Affinity Capture-MS Homo sapiens 33 CDK12 51755 Affinity Capture-MS Homo sapiens 34 ERC1 23085 Affinity Capture-MS Homo sapiens 35 PCMTD2   Affinity Capture-MS Homo sapiens 36 MDC1   Affinity Capture-MS Homo sapiens 37 ZGPAT   Affinity Capture-MS Homo sapiens 38 ETV4   Proximity Label-MS Homo sapiens 39 CALCOCO2   Two-hybrid Homo sapiens 40 KLF15   Proximity Label-MS Homo sapiens 41 HMGA1 3159 Affinity Capture-MS Homo sapiens 42 BCORL1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 43 POU5F1   Affinity Capture-MS Homo sapiens 44 BCOR   Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens Reconstituted Complex Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens Co-purification Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 45 TIAL1 7073 Affinity Capture-MS Homo sapiens 46 TOR3A 64222 Affinity Capture-MS Homo sapiens 47 LHX4   Proximity Label-MS Homo sapiens 48 MLLT1 4298 Affinity Capture-MS Homo sapiens 49 USP7 7874 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 50 CSNK2B 1460 Affinity Capture-MS Homo sapiens 51 SOX5 6660 Proximity Label-MS Homo sapiens 52 EBF1   Affinity Capture-MS Homo sapiens 53 YAF2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 54 CBX3 11335 Affinity Capture-MS Homo sapiens 55 KLF16   Proximity Label-MS Homo sapiens 56 ING4   Affinity Capture-MS Homo sapiens 57 PRDM1   Proximity Label-MS Homo sapiens 58 HIST1H4A 8359 Affinity Capture-MS Homo sapiens 59 TLX3   Proximity Label-MS Homo sapiens 60 NAA50 80218 Affinity Capture-MS Homo sapiens 61 MRE11A 4361 Affinity Capture-MS Homo sapiens 62 ERBB3 2065 Affinity Capture-MS Homo sapiens 63 HIST1H2AG 8969 Affinity Capture-MS Homo sapiens 64 XRCC5 7520 Co-localization Homo sapiens 65 TBR1   Proximity Label-MS Homo sapiens 66 MGA   Affinity Capture-MS Homo sapiens 67 NFIX 4784 Proximity Label-MS Homo sapiens 68 SRRT 51593 Affinity Capture-MS Homo sapiens 69 DPPA2   Affinity Capture-MS Homo sapiens 70 Ring1   Affinity Capture-MS Mus musculus 71 HIST1H2AM 8336 Affinity Capture-MS Homo sapiens 72 CBX4   Affinity Capture-MS Homo sapiens 73 CHMP4B 128866 Affinity Capture-MS Homo sapiens 74 GATA3   Proximity Label-MS Homo sapiens 75 SIPA1L2   Affinity Capture-MS Homo sapiens 76 DDB1 1642 Affinity Capture-MS Homo sapiens 77 LHX8   Proximity Label-MS Homo sapiens 78 PAX8   Proximity Label-MS Homo sapiens 79 LETMD1   Affinity Capture-MS Homo sapiens 80 UBE2D3 7323 Reconstituted Complex Homo sapiens 81 GATA2   Proximity Label-MS Homo sapiens 82 T   Proximity Label-MS Homo sapiens 83 RNF125   Two-hybrid Homo sapiens 84 H2AFX 3014 Affinity Capture-Western Homo sapiens Co-localization Homo sapiens Affinity Capture-MS Homo sapiens 85 KLF12   Proximity Label-MS Homo sapiens 86 SOX17   Proximity Label-MS Homo sapiens 87 ZNF609   Affinity Capture-MS Homo sapiens 88 SMARCC2 6601 Affinity Capture-MS Homo sapiens 89 HIST1H2AI 8329 Affinity Capture-MS Homo sapiens 90 SSBP3   Affinity Capture-MS Homo sapiens 91 RING1 6015 Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Reconstituted Complex Homo sapiens Affinity Capture-MS Homo sapiens Two-hybrid Homo sapiens Affinity Capture-MS Homo sapiens Co-purification Homo sapiens Affinity Capture-MS Homo sapiens 92 PPP2R3A   Affinity Capture-MS Homo sapiens 93 CARD14   Affinity Capture-MS Homo sapiens 94 PAX6   Proximity Label-MS Homo sapiens 95 USP42   Affinity Capture-MS Homo sapiens 96 POLE2   Affinity Capture-MS Homo sapiens 97 HIST1H2AL 8332 Affinity Capture-MS Homo sapiens 98 TP53BP1 7158 Affinity Capture-MS Homo sapiens 99 SOX6   Proximity Label-MS Homo sapiens 100 PIP 5304 Affinity Capture-MS Homo sapiens 101 RAB13 5872 Affinity Capture-MS Homo sapiens 102 ELK3   Proximity Label-MS Homo sapiens 103 AKAP9 10142 Affinity Capture-MS Homo sapiens 104 PPP6C 5537 Affinity Capture-MS Homo sapiens 105 ELP3 55140 Affinity Capture-MS Homo sapiens 106 FOXI1   Proximity Label-MS Homo sapiens 107 ERCC8   Affinity Capture-MS Homo sapiens 108 SPECC1 92521 Affinity Capture-MS Homo sapiens 109 FOXL1   Proximity Label-MS Homo sapiens 110 PHC3   Affinity Capture-MS Homo sapiens 111 CBX2   Affinity Capture-MS Homo sapiens 112 SUZ12   Affinity Capture-MS Homo sapiens 113 SASS6 163786 Affinity Capture-MS Homo sapiens 114 ARID1B 57492 Affinity Capture-MS Homo sapiens 115 HNF4A   Proximity Label-MS Homo sapiens 116 CBX6   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 117 FABP5 2171 Affinity Capture-MS Homo sapiens 118 ZNF157   Affinity Capture-MS Homo sapiens 119 CSNK2A2 1459 Affinity Capture-MS Homo sapiens 120 PHC1   Affinity Capture-MS Homo sapiens 121 ZDHHC18 84243 Affinity Capture-MS Homo sapiens 122 EED   Affinity Capture-MS Homo sapiens 123 HSPA4 3308 Affinity Capture-MS Homo sapiens 124 PCGF1 84759 Biochemical Activity Homo sapiens Affinity Capture-MS Homo sapiens Biochemical Activity Homo sapiens Affinity Capture-MS Homo sapiens 125 RNF2   Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens Reconstituted Complex Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens Two-hybrid Homo sapiens Reconstituted Complex Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens Two-hybrid Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Reconstituted Complex Homo sapiens 126 BMI1   Co-purification Homo sapiens Affinity Capture-MS Homo sapiens 127 PATZ1   Affinity Capture-MS Homo sapiens 128 PGAM1 5223 Affinity Capture-MS Homo sapiens 129 SCMH1   Affinity Capture-MS Homo sapiens 130 NANOG   Affinity Capture-MS Homo sapiens Co-purification Homo sapiens 131 NFIC 4782 Proximity Label-MS Homo sapiens 132 UBE2U   Two-hybrid Homo sapiens 133 CBX7   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 134 STAT4   Proximity Label-MS Homo sapiens 135 CDAN1 146059 Affinity Capture-MS Homo sapiens 136 TLX1   Proximity Label-MS Homo sapiens 137 TUBGCP2 10844 Affinity Capture-MS Homo sapiens 138 TERF2   Affinity Capture-MS Homo sapiens 139 DIDO1   Affinity Capture-MS Homo sapiens 140 NSF 4905 Affinity Capture-MS Homo sapiens 141 USP34 9736 Affinity Capture-MS Homo sapiens 142 TP53 7157 Negative Genetic Homo sapiens 143 SATB2   Affinity Capture-MS Homo sapiens 144 L3MBTL2   Affinity Capture-MS Homo sapiens 145 PCMT1 5110 Affinity Capture-MS Homo sapiens 146 PCGF6   Affinity Capture-MS Homo sapiens 147 SAP18 10284 Affinity Capture-MS Homo sapiens 148 KLF3   Proximity Label-MS Homo sapiens 149 SKP1 6500 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Co-purification Homo sapiens 150 ATG101   Affinity Capture-MS Homo sapiens 151 TCERG1 10915 Affinity Capture-MS Homo sapiens 152 HMGA2 8091 Affinity Capture-MS Homo sapiens 153 ITPR3 3710 Affinity Capture-MS Homo sapiens 154 ZDHHC23   Affinity Capture-MS Homo sapiens 155 HSP90AA1 3320 Affinity Capture-Luminescence Homo sapiens 156 PAX9   Proximity Label-MS Homo sapiens 157 PCGF3   Affinity Capture-MS Homo sapiens 158 PRAM1   Affinity Capture-MS Homo sapiens 159 KLF5   Proximity Label-MS Homo sapiens 160 TXN 7295 Affinity Capture-MS Homo sapiens 161 PAX7   Proximity Label-MS Homo sapiens 162 HIST1H2AK 8330 Affinity Capture-MS Homo sapiens 163 EZH2   Co-purification Homo sapiens 164 RYBP   Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens 165 IBTK 25998 Affinity Capture-MS Homo sapiens 166 UPF1 5976 Affinity Capture-MS Homo sapiens 167 CBX8 57332 Affinity Capture-MS Homo sapiens Co-purification Homo sapiens Affinity Capture-MS Homo sapiens 168 HIST1H2AB 8335 Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens 169 ACACB 32 Affinity Capture-MS Homo sapiens 170 MLLT3 4300 Affinity Capture-MS Homo sapiens 171 ERG   Proximity Label-MS Homo sapiens 172 HNF1B   Proximity Label-MS Homo sapiens 173 KDM2B 84678 Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens Co-purification Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens 174 AR 367 Proximity Label-MS Homo sapiens 175 PHC2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 176 FBXO38 81545 Proximity Label-MS Homo sapiens 177 SP7   Proximity Label-MS Homo sapiens 178 PDCD7   Affinity Capture-MS Homo sapiens View the network

Pathways in which PCGF1 is involved

No pathways found