Gene description for KMT2D
Gene name	lysine (K)-specific methyltransferase 2D
Gene symbol	KMT2D
Other names/aliases	AAD10 ALR CAGL114 KABUK1 KMS MLL2 MLL4 TNRC21
Species	Homo sapiens
Database cross references - KMT2D
ExoCarta	ExoCarta_8085
Vesiclepedia	VP_8085
Entrez Gene	8085
HGNC	7133
MIM	602113
UniProt	O14686
KMT2D identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells	25944692
Urine	22418980
Urine	22418980

Gene ontology annotations for KMT2D

Molecular Function     transcription cis-regulatory region binding GO:0000976 IDA     DNA binding GO:0003677 NAS     transcription coactivator activity GO:0003713 IBA     protein binding GO:0005515 IPI     histone H3K4 methyltransferase activity GO:0042800 IBA     histone H3K4 methyltransferase activity GO:0042800 ISS     histone H3K4 methyltransferase activity GO:0042800 TAS     metal ion binding GO:0046872 IEA     histone H3K4 monomethyltransferase activity GO:0140945 IEA     histone H3K4 trimethyltransferase activity GO:0140999 IEA Biological Process     oocyte growth GO:0001555 ISS     regulation of DNA-templated transcription GO:0006355 NAS     positive regulation of cell population proliferation GO:0008284 IMP     heterochromatin formation GO:0031507 ISS     methylation GO:0032259 IEA     positive regulation of intracellular estrogen receptor signaling pathway GO:0033148 IMP     response to estrogen GO:0043627 IDA     positive regulation of transcription by RNA polymerase II GO:0045944 IBA     positive regulation of transcription by RNA polymerase II GO:0045944 IMP     oogenesis GO:0048477 ISS     beta-catenin-TCF complex assembly GO:1904837 TAS Subcellular Localization     nucleus GO:0005634 NAS     nucleoplasm GO:0005654 TAS     MLL3/4 complex GO:0044666 IBA     MLL3/4 complex GO:0044666 IDA     MLL3/4 complex GO:0044666 IPI