Gene description for MAZ
Gene name
MYC-associated zinc finger protein (purine-binding transcription factor)
Gene symbol
MAZ
Other names/aliases
PUR1 Pur-1 SAF-1 SAF-2 SAF-3 ZF87 ZNF801 Zif87
Species
Homo sapiens
Database cross references - MAZ
ExoCarta
ExoCarta_4150
Entrez Gene
4150
HGNC
6914
MIM
600999
UniProt
P56270
MAZ identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells
26054723
Hepatocellular carcinoma cells
26054723
Gene ontology annotations for MAZ
Experiment description of studies that identified MAZ in exosomes
1
Experiment ID
235
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
✘
EV Membrane markers
✔
HSP90B1
EV Negative markers
✔
qNano
EV Particle analysis
Identified molecule
mRNA
Identification method
RNA Sequencing
PubMed ID
26054723
Organism
Homo sapiens
Experiment description
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors
He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name
Carcinogenesis
Publication year
2015
Sample
Hepatocellular carcinoma cells
Sample name
HKCI-8
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.13-1.19 g/mL
Molecules identified in the study
Protein RNA
Methods used in the study
Western blotting Mass spectrometry RT-PCR RNA Sequencing
2
Experiment ID
236
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
✘
EV Membrane markers
✔
HSP90B1
EV Negative markers
✔
qNano
EV Particle analysis
Identified molecule
mRNA
Identification method
RNA Sequencing
PubMed ID
26054723
Organism
Homo sapiens
Experiment description
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors
He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name
Carcinogenesis
Publication year
2015
Sample
Hepatocellular carcinoma cells
Sample name
MHCC97L
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.13-1.19 g/mL
Molecules identified in the study
Protein RNA
Methods used in the study
Western blotting Mass spectrometry RT-PCR RNA Sequencing
Protein-protein interactions for MAZ
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
DCC
Invivo
Homo sapiens
Invitro
Homo sapiens
Two-hybrid
Homo sapiens
2
CSNK2A1
1457
Biochemical Activity
Homo sapiens
3
BPTF
2186
Two-hybrid
Homo sapiens
Reconstituted Complex
Homo sapiens
Reconstituted Complex
Homo sapiens
View the network
image/svg+xml
Pathways in which MAZ is involved
No pathways found