Gene description for THOC7
Gene name THO complex 7
Gene symbol THOC7
Other names/aliases NIF3L1BP1
Species Homo sapiens
 Database cross references - THOC7
ExoCarta ExoCarta_80145
Entrez Gene 80145
HGNC 29874
MIM 611965
UniProt Q6I9Y2  
 THOC7 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for THOC7
Molecular Function
    RNA binding GO:0003723 IEA
    protein binding GO:0005515 IPI
Biological Process
    RNA splicing GO:0008380 IEA
    mRNA export from nucleus GO:0006406 IDA
    viral mRNA export from host cell nucleus GO:0046784 IDA
    mRNA processing GO:0006397 IEA
Subcellular Localization
    THO complex GO:0000347 IDA
    cytoplasm GO:0005737 IDA
    nuclear speck GO:0016607 IEA
    nucleoplasm GO:0005654 IDA
    THO complex part of transcription export complex GO:0000445 IDA
    transcription export complex GO:0000346 IDA
    nucleus GO:0005634 IDA
 Experiment description of studies that identified THOC7 in exosomes
Experiment ID 217
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for THOC7
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 MED18  
Reconstituted Complex Homo sapiens
2 GOT2 2806
Two-hybrid Homo sapiens
3 MED8  
Reconstituted Complex Homo sapiens
4 NIF3L1 60491
Two-hybrid Homo sapiens
5 SURF5  
Reconstituted Complex Homo sapiens
6 CHD3  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which THOC7 is involved
No pathways found

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