Gene description for SLC13A2
Gene name solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
Gene symbol SLC13A2
Other names/aliases NADC1
NaCT
NaDC-1
SDCT1
Species Homo sapiens
 Database cross references - SLC13A2
ExoCarta ExoCarta_9058
Entrez Gene 9058
HGNC 10917
MIM 604148
UniProt Q13183  
 SLC13A2 identified in exosomes derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for SLC13A2
Molecular Function
    low-affinity sodium:dicarboxylate symporter activity GO:0015361 TAS
Biological Process
    dicarboxylic acid transport GO:0006835 TAS
    transport GO:0006810 TAS
    transmembrane transport GO:0055085 TAS
    sodium ion transport GO:0006814 IEA
Subcellular Localization
    plasma membrane GO:0005886 TAS
    membrane GO:0016020 TAS
    extracellular exosome GO:0070062 IDA
    integral component of plasma membrane GO:0005887 TAS
 Experiment description of studies that identified SLC13A2 in exosomes
1
Experiment ID 63
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✔
AQP2
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for SLC13A2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which SLC13A2 is involved
PathwayEvidenceSource
Sodium-coupled sulphate, di- and tri-carboxylate transporters TAS Reactome





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