Gene description for PCNXL3
Gene name pecanex-like 3 (Drosophila)
Gene symbol PCNXL3
Other names/aliases -
Species Homo sapiens
 Database cross references - PCNXL3
ExoCarta ExoCarta_399909
Vesiclepedia VP_399909
Entrez Gene 399909
HGNC 18760
UniProt Q9H6A9  
 PCNXL3 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for PCNXL3
Molecular Function
    protein binding GO:0005515 IPI
Subcellular Localization
    membrane GO:0016020 IEA
 Experiment description of studies that identified PCNXL3 in exosomes
1
Experiment ID 489
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for PCNXL3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 RXFP1  
Affinity Capture-MS Homo sapiens
2 HTR3A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 LIMA1 51474
Affinity Capture-MS Homo sapiens
4 FAM189B  
Affinity Capture-MS Homo sapiens
5 SLC17A2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 TMEM107 84314
Affinity Capture-MS Homo sapiens
7 TTYH1  
Affinity Capture-MS Homo sapiens
8 KCNA2  
Affinity Capture-MS Homo sapiens
9 PTH1R  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 OCLN 100506658
Proximity Label-MS Homo sapiens
11 TSPAN17 26262
Affinity Capture-MS Homo sapiens
12 SVIL 6840
Two-hybrid Homo sapiens
13 OR10H2  
Affinity Capture-MS Homo sapiens
14 PIGO  
Affinity Capture-MS Homo sapiens
15 SLC45A2 51151
Affinity Capture-MS Homo sapiens
16 Cdh1 12550
Affinity Capture-MS Mus musculus
17 SLC13A2 9058
Affinity Capture-MS Homo sapiens
18 HCST  
Affinity Capture-MS Homo sapiens
19 ZDHHC12  
Affinity Capture-MS Homo sapiens
20 KCNK18  
Affinity Capture-MS Homo sapiens
21 SYNGR1 9145
Affinity Capture-MS Homo sapiens
22 PIGH  
Affinity Capture-MS Homo sapiens
23 TSPAN15 23555
Affinity Capture-MS Homo sapiens
24 GJA1 2697
Proximity Label-MS Homo sapiens
25 NAT8B  
Affinity Capture-MS Homo sapiens
26 CHRNA7  
Affinity Capture-MS Homo sapiens
27 FCER1A  
Affinity Capture-MS Homo sapiens
28 SKP2  
Affinity Capture-MS Homo sapiens
29 SCAP  
Affinity Capture-MS Homo sapiens
30 SOX2  
Affinity Capture-MS Homo sapiens
31 GABRA6  
Affinity Capture-MS Homo sapiens
32 MCAM 4162
Proximity Label-MS Homo sapiens
33 KCNE3  
Affinity Capture-MS Homo sapiens
34 MS4A15  
Affinity Capture-MS Homo sapiens
35 RAET1L  
Affinity Capture-MS Homo sapiens
36 CYP19A1  
Affinity Capture-MS Homo sapiens
37 DIRAS3  
Proximity Label-MS Homo sapiens
38 TMEM31  
Affinity Capture-MS Homo sapiens
39 ZNRF4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 ATP2B2 491
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
41 LRRTM1 347730
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
42 SLC4A8 9498
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
43 TM2D2 83877
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
44 FAM189A2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
45 MARCH4  
Affinity Capture-MS Homo sapiens
46 RHOB 388
Proximity Label-MS Homo sapiens
47 YIPF3 25844
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
48 Coro1c 23790
Affinity Capture-MS Mus musculus
49 RNF185  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
50 CHRNB1  
Affinity Capture-MS Homo sapiens
51 MRAP2  
Affinity Capture-MS Homo sapiens
52 KCNC3 3748
Affinity Capture-MS Homo sapiens
53 TRPM8  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
54 C3orf52  
Affinity Capture-MS Homo sapiens
55 TM2D1 83941
Affinity Capture-MS Homo sapiens
56 PCDHAC2  
Affinity Capture-MS Homo sapiens
57 POPDC2  
Affinity Capture-MS Homo sapiens
58 CLRN2  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which PCNXL3 is involved
No pathways found





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