Gene description for TMEM107
Gene name transmembrane protein 107
Gene symbol TMEM107
Other names/aliases GRVS638
PRO1268
Species Homo sapiens
 Database cross references - TMEM107
ExoCarta ExoCarta_84314
Entrez Gene 84314
HGNC 28128
MIM 616183
UniProt Q6UX40  
 TMEM107 identified in exosomes derived from the following tissue/cell type
Endothelial cells 26027894    
 Gene ontology annotations for TMEM107
Molecular Function
    molecular_function GO:0003674 ND
Biological Process
    cilium assembly GO:0042384 ISS
    neural tube patterning GO:0021532 IEA
    biological_process GO:0008150 ND
    embryonic digit morphogenesis GO:0042733 IEA
Subcellular Localization
    integral component of membrane GO:0016021 IEA
    cellular_component GO:0005575 ND
 Experiment description of studies that identified TMEM107 in exosomes
1
Experiment ID 226
ISEV standards
EM
EV Biophysical techniques
GAPDH
EV Cytosolic markers
CD9|FLOT1
EV Membrane markers
LMNA|H2AFX|ATP5A1|TOMM20
EV Negative markers
EV Particle analysis
Identified molecule mRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting
Authors Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
 Protein-protein interactions for TMEM107
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which TMEM107 is involved
No pathways found





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