Gene description for SYNGR1
Gene name synaptogyrin 1
Gene symbol SYNGR1
Other names/aliases -
Species Homo sapiens
 Database cross references - SYNGR1
ExoCarta ExoCarta_9145
Entrez Gene 9145
HGNC 11498
MIM 603925
UniProt O43759  
 SYNGR1 identified in exosomes derived from the following tissue/cell type
Melanoma cells 25950383    
 Gene ontology annotations for SYNGR1
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    regulation of long-term neuronal synaptic plasticity GO:0048169 ISS
    protein targeting GO:0006605 IEA
    regulation of short-term neuronal synaptic plasticity GO:0048172 ISS
Subcellular Localization
    neuromuscular junction GO:0031594 IBA
    integral component of membrane GO:0016021 NAS
    synaptic vesicle membrane GO:0030672 IBA
    melanosome GO:0042470 IEA
    cell junction GO:0030054 IEA
 Experiment description of studies that identified SYNGR1 in exosomes
1
Experiment ID 258
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
FLOT1|CD81
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name SKMEL28
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for SYNGR1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which SYNGR1 is involved
No pathways found





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