Gene description for ZDHHC13
Gene name zinc finger, DHHC-type containing 13
Gene symbol ZDHHC13
Other names/aliases HIP14L
HIP3RP
Species Homo sapiens
 Database cross references - ZDHHC13
ExoCarta ExoCarta_54503
Entrez Gene 54503
HGNC 18413
MIM 612815
UniProt Q8IUH4  
 ZDHHC13 identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
 Gene ontology annotations for ZDHHC13
Molecular Function
    palmitoyltransferase activity GO:0016409 ISS
    magnesium ion transmembrane transporter activity GO:0015095 ISS
    zinc ion binding GO:0008270 IEA
    signal transducer activity GO:0004871 IMP
    protein-cysteine S-palmitoyltransferase activity GO:0019706 IEA
Biological Process
    positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 IMP
    magnesium ion transport GO:0015693 IEA
    metabolic process GO:0008152 ISS
    signal transduction GO:0007165 IMP
Subcellular Localization
    endoplasmic reticulum GO:0005783 IDA
    intracellular membrane-bounded organelle GO:0043231 IDA
    Golgi membrane GO:0000139 ISS
    Golgi-associated vesicle membrane GO:0030660 ISS
    membrane GO:0016020 IDA
    Golgi apparatus GO:0005794 IDA
    integral component of membrane GO:0016021 IEA
 Experiment description of studies that identified ZDHHC13 in exosomes
1
Experiment ID 211
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
EpCAM|TFRC
EV Membrane markers
✔
cytochrome c|GOLGA2
EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 212
ISEV standards
✔
CEM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
EpCAM|TFRC
EV Membrane markers
✔
Cytochrome C|GOLGA2
EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ZDHHC13
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ZDHHC13 is involved
No pathways found





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