Gene description for ZDHHC13
Gene name zinc finger, DHHC-type containing 13
Gene symbol ZDHHC13
Other names/aliases HIP14L
HIP3RP
Species Homo sapiens
 Database cross references - ZDHHC13
ExoCarta ExoCarta_54503
Vesiclepedia VP_54503
Entrez Gene 54503
HGNC 18413
MIM 612815
UniProt Q8IUH4  
 ZDHHC13 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
 Gene ontology annotations for ZDHHC13
Molecular Function
    magnesium ion transmembrane transporter activity GO:0015095 ISS
    palmitoyltransferase activity GO:0016409 ISS
Biological Process
    positive regulation of canonical NF-kappaB signal transduction GO:0043123 HMP
    magnesium ion transmembrane transport GO:1903830 IEA
Subcellular Localization
    Golgi membrane GO:0000139 ISS
    endoplasmic reticulum GO:0005783 IDA
    membrane GO:0016020 HDA
    Golgi-associated vesicle membrane GO:0030660 ISS
 Experiment description of studies that identified ZDHHC13 in exosomes
1
Experiment ID 489
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 211
MISEV standards
EM
Biophysical techniques
TSG101|Alix|EpCAM|TFRC
Enriched markers
cytochrome c|GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
6
Experiment ID 212
MISEV standards
CEM
Biophysical techniques
TSG101|Alix|EpCAM|TFRC
Enriched markers
Cytochrome C|GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ZDHHC13
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 RNF149 284996
Affinity Capture-MS Homo sapiens
2 TACR3  
Affinity Capture-MS Homo sapiens
3 CRLF2 64109
Affinity Capture-MS Homo sapiens
4 STARD3NL 83930
Affinity Capture-MS Homo sapiens
5 VIPR2  
Affinity Capture-MS Homo sapiens
6 ATP13A3 79572
Affinity Capture-MS Homo sapiens
7 TMEM9 252839
Affinity Capture-MS Homo sapiens
8 SPRY2 10253
Affinity Capture-MS Homo sapiens
9 GPR17 2840
Affinity Capture-MS Homo sapiens
10 SPRED2 200734
Affinity Capture-MS Homo sapiens
11 SYNGR1 9145
Affinity Capture-MS Homo sapiens
12 C3AR1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 CD83  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
14 TRIM66  
Affinity Capture-MS Homo sapiens
15 ARSE 415
Affinity Capture-MS Homo sapiens
16 PLSCR4  
Affinity Capture-MS Homo sapiens
17 CX3CL1  
Affinity Capture-MS Homo sapiens
18 TSPAN15 23555
Affinity Capture-MS Homo sapiens
19 TSPAN18 90139
Affinity Capture-MS Homo sapiens
20 WBP1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
21 PLAC8L1  
Affinity Capture-MS Homo sapiens
22 DDX58 23586
Affinity Capture-RNA Homo sapiens
23 SCAP  
Affinity Capture-MS Homo sapiens
24 LPAR1 1902
Affinity Capture-MS Homo sapiens
25 CTXN1  
Affinity Capture-MS Homo sapiens
26 GPR35  
Affinity Capture-MS Homo sapiens
27 KRTCAP3 200634
Affinity Capture-MS Homo sapiens
28 DNAJC5 80331
Affinity Capture-MS Homo sapiens
29 PLD3 23646
Affinity Capture-MS Homo sapiens
30 DNAJC5B  
Affinity Capture-MS Homo sapiens
31 RAB7A 7879
Proximity Label-MS Homo sapiens
32 SCGN  
Affinity Capture-MS Homo sapiens
33 ACRBP  
Affinity Capture-MS Homo sapiens
34 IPPK  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
35 TMED2 10959
Affinity Capture-MS Homo sapiens
36 VIPR1  
Affinity Capture-MS Homo sapiens
37 B3GAT3 26229
Affinity Capture-MS Homo sapiens
38 CCR6  
Affinity Capture-MS Homo sapiens
39 S1PR4  
Affinity Capture-MS Homo sapiens
40 PIGH  
Affinity Capture-MS Homo sapiens
41 SPINT2 10653
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
42 MRAP2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
43 FFAR1  
Affinity Capture-MS Homo sapiens
44 DGCR2 9993
Affinity Capture-MS Homo sapiens
45 SPRY4 81848
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which ZDHHC13 is involved
No pathways found





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