Gene description for ARSE
Gene name arylsulfatase E (chondrodysplasia punctata 1)
Gene symbol ARSE
Other names/aliases ASE
CDPX
CDPX1
CDPXR
Species Homo sapiens
 Database cross references - ARSE
ExoCarta ExoCarta_415
Vesiclepedia VP_415
Entrez Gene 415
HGNC 719
MIM 300180
UniProt P51690  
 ARSE identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Urine 19056867    
 Gene ontology annotations for ARSE
Molecular Function
    arylsulfatase activity GO:0004065 IBA
    arylsulfatase activity GO:0004065 IDA
    metal ion binding GO:0046872 IEA
Biological Process
    skeletal system development GO:0001501 TAS
Subcellular Localization
    endoplasmic reticulum lumen GO:0005788 TAS
    Golgi apparatus GO:0005794 IDA
    Golgi stack GO:0005795 IEA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified ARSE in exosomes
1
Experiment ID 489
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 63
MISEV standards
Biophysical techniques
AQP2
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for ARSE
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ARSD  
Affinity Capture-MS Homo sapiens
2 SQRDL 58472
Affinity Capture-MS Homo sapiens
3 RHBDD1 84236
Affinity Capture-MS Homo sapiens
4 FZD2 2535
Affinity Capture-MS Homo sapiens
5 SELT 51714
Affinity Capture-MS Homo sapiens
6 TMEM39B  
Affinity Capture-MS Homo sapiens
7 TMEM214 54867
Affinity Capture-MS Homo sapiens
8 VAC14 55697
Affinity Capture-MS Homo sapiens
9 DSTYK 25778
Affinity Capture-MS Homo sapiens
10 ZDHHC17 23390
Affinity Capture-MS Homo sapiens
11 FBXO21  
Affinity Capture-MS Homo sapiens
12 COQ6 51004
Two-hybrid Homo sapiens
13 GLB1L2  
Affinity Capture-MS Homo sapiens
14 ZDHHC13 54503
Affinity Capture-MS Homo sapiens
15 FKBP14  
Affinity Capture-MS Homo sapiens
16 NIN 51199
Affinity Capture-MS Homo sapiens
17 MTOR 2475
Affinity Capture-MS Homo sapiens
18 LMF2 91289
Affinity Capture-MS Homo sapiens
19 CLPTM1L 81037
Affinity Capture-MS Homo sapiens
20 SUMF1 285362
Affinity Capture-MS Homo sapiens
21 SEMA4F  
Affinity Capture-MS Homo sapiens
22 PIGH  
Affinity Capture-MS Homo sapiens
23 NUS1  
Affinity Capture-MS Homo sapiens
24 NDN 4692
Two-hybrid Homo sapiens
View the network image/svg+xml



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