Gene description for RER1
Gene name retention in endoplasmic reticulum sorting receptor 1
Gene symbol RER1
Other names/aliases -
Species Homo sapiens
 Database cross references - RER1
ExoCarta ExoCarta_11079
Entrez Gene 11079
HGNC 30309
UniProt O15258  
 RER1 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for RER1
Molecular Function
    acetylcholine receptor binding GO:0033130 IEA
    molecular_function GO:0003674 ND
Biological Process
    positive regulation of establishment of protein localization to plasma membrane GO:0090004 IEA
    retrograde vesicle-mediated transport, Golgi to ER GO:0006890 IDA
    skeletal muscle acetylcholine-gated channel clustering GO:0071340 IEA
Subcellular Localization
    Golgi apparatus GO:0005794 IDA
    cell surface GO:0009986 IEA
    endoplasmic reticulum-Golgi intermediate compartment GO:0005793 IEA
    integral component of Golgi membrane GO:0030173 IDA
 Experiment description of studies that identified RER1 in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for RER1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 IMMT 10989
Two-hybrid Homo sapiens
2 SH3GL3  
Two-hybrid Homo sapiens
3 HAP1  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which RER1 is involved
No pathways found





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