Gene description for ATP5I
Gene name ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E
Gene symbol ATP5I
Other names/aliases ATP5K
Species Homo sapiens
 Database cross references - ATP5I
ExoCarta ExoCarta_521
Entrez Gene 521
HGNC 846
MIM 601519
UniProt P56385  
 ATP5I identified in exosomes derived from the following tissue/cell type
Colorectal cancer cells 17956143    
 Gene ontology annotations for ATP5I
Molecular Function
    hydrogen ion transmembrane transporter activity GO:0015078 IEA
    transmembrane transporter activity GO:0022857 IC
    ATPase activity GO:0016887 IDA
Biological Process
    mitochondrial ATP synthesis coupled proton transport GO:0042776 TAS
    small molecule metabolic process GO:0044281 TAS
    respiratory electron transport chain GO:0022904 TAS
    cellular metabolic process GO:0044237 TAS
Subcellular Localization
    mitochondrion GO:0005739 IDA
    mitochondrial proton-transporting ATP synthase complex GO:0005753 IDA
    mitochondrial inner membrane GO:0005743 TAS
    mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) GO:0000276 IEA
 Experiment description of studies that identified ATP5I in exosomes
1
Experiment ID 20
ISEV standards
EM
EV Biophysical techniques
HSP90
EV Cytosolic markers
CD63|CD81|LAMP1
EV Membrane markers
GOLGA2|cytochrome c
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17956143    
Organism Homo sapiens
Experiment description Proteomic analysis of microvesicles derived from human colorectal cancer cells.
Authors Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS
Journal name JPR
Publication year 2007
Sample Colorectal cancer cells
Sample name HT29
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Diafiltration
Flotation density 1.16 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for ATP5I
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ATP5I is involved
PathwayEvidenceSource
Formation of ATP by chemiosmotic coupling TAS Reactome





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