Gene description for PILRB
Gene name paired immunoglobin-like type 2 receptor beta
Gene symbol PILRB
Other names/aliases FDFACT1
FDFACT2
Species Homo sapiens
 Database cross references - PILRB
ExoCarta ExoCarta_29990
Vesiclepedia VP_29990
Entrez Gene 29990
HGNC 18297
MIM 605342
UniProt Q9UKJ0  
 PILRB identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for PILRB
Molecular Function
    protein binding GO:0005515 IPI
    MHC class I protein binding GO:0042288 IBA
Biological Process
    cell surface receptor protein tyrosine kinase signaling pathway GO:0007169 TAS
    activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 NAS
Subcellular Localization
    plasma membrane GO:0005886 NAS
    plasma membrane GO:0005886 TAS
 Experiment description of studies that identified PILRB in exosomes
1
Experiment ID 236
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for PILRB
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SGCB 6443
Affinity Capture-MS Homo sapiens
2 HNRNPH1 3187
Affinity Capture-RNA Homo sapiens
3 REEP5 7905
Affinity Capture-MS Homo sapiens
4 NME2 4831
Affinity Capture-MS Homo sapiens
5 SLC19A2 10560
Affinity Capture-MS Homo sapiens
6 C4orf32  
Affinity Capture-MS Homo sapiens
7 ATP6AP1 537
Affinity Capture-MS Homo sapiens
8 ATP6AP2 10159
Affinity Capture-MS Homo sapiens
9 ATP5I 521
Affinity Capture-MS Homo sapiens
10 TTYH3 80727
Affinity Capture-MS Homo sapiens
11 GALNT1 2589
Affinity Capture-MS Homo sapiens
12 SLC35F2 54733
Affinity Capture-MS Homo sapiens
13 BRCA1 672
Two-hybrid Homo sapiens
14 POMGNT1 55624
Affinity Capture-MS Homo sapiens
15 TSPAN15 23555
Affinity Capture-MS Homo sapiens
16 ATP5F1 515
Affinity Capture-MS Homo sapiens
17 TTYH2 94015
Affinity Capture-MS Homo sapiens
18 NDUFAF1  
Affinity Capture-MS Homo sapiens
19 ATP6V0C 527
Affinity Capture-MS Homo sapiens
20 DDX58 23586
Affinity Capture-RNA Homo sapiens
21 RTN4 57142
Affinity Capture-MS Homo sapiens
22 ATP5L 10632
Affinity Capture-MS Homo sapiens
23 TMEM70  
Affinity Capture-MS Homo sapiens
24 ATP5G1  
Affinity Capture-MS Homo sapiens
25 CERS2 29956
Affinity Capture-MS Homo sapiens
26 KDSR 2531
Affinity Capture-MS Homo sapiens
27 HSP90AA4P 3323
Affinity Capture-MS Homo sapiens
28 TAPBP 6892
Affinity Capture-MS Homo sapiens
29 ATP12A 479
Affinity Capture-MS Homo sapiens
30 PILRA 29992
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
31 ASIC1  
Affinity Capture-MS Homo sapiens
32 EI24  
Affinity Capture-MS Homo sapiens
33 ATP5C1 509
Affinity Capture-MS Homo sapiens
34 VMA21  
Affinity Capture-MS Homo sapiens
35 DYM  
Affinity Capture-MS Homo sapiens
36 C10orf35  
Affinity Capture-MS Homo sapiens
37 ATP8  
Affinity Capture-MS Homo sapiens
38 ATP5O 539
Affinity Capture-MS Homo sapiens
39 ATP5B 506
Affinity Capture-MS Homo sapiens
40 REEP6  
Affinity Capture-MS Homo sapiens
41 ATP5A1 498
Affinity Capture-MS Homo sapiens
42 YIF1B 90522
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



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