Gene description for PILRB
Gene name paired immunoglobin-like type 2 receptor beta
Gene symbol PILRB
Other names/aliases FDFACT1
FDFACT2
Species Homo sapiens
 Database cross references - PILRB
ExoCarta ExoCarta_29990
Entrez Gene 29990
HGNC 18297
MIM 605342
UniProt Q9UKJ0  
 PILRB identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for PILRB
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 NAS
    transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 TAS
Subcellular Localization
    integral component of plasma membrane GO:0005887 NAS
 Experiment description of studies that identified PILRB in exosomes
1
Experiment ID 236
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for PILRB
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PILRB is involved
No pathways found





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