Gene description for PRKCI
Gene name	protein kinase C, iota
Gene symbol	PRKCI
Other names/aliases	DXS1179E PKCI nPKC-iota
Species	Homo sapiens
Database cross references - PRKCI
ExoCarta	ExoCarta_5584
Entrez Gene	5584
HGNC	9404
MIM	600539
UniProt	P41743
PRKCI identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells	23333927
Ovarian cancer cells	23333927
Urine	19056867

Gene ontology annotations for PRKCI

Molecular Function     protein binding GO:0005515 IPI     protein kinase C activity GO:0004697 ISS     protein domain specific binding GO:0019904 IEA     metal ion binding GO:0046872 IEA     protein serine/threonine kinase activity GO:0004674 TAS     ATP binding GO:0005524 TAS     phospholipid binding GO:0005543 IDA     protein kinase activity GO:0004672 IDA Biological Process     establishment of apical/basal cell polarity GO:0035089 IEA     protein targeting to membrane GO:0006612 NAS     intracellular signal transduction GO:0035556 IEA     response to interleukin-1 GO:0070555 IEA     cytoskeleton organization GO:0007010 NAS     establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 TAS     positive regulation of endothelial cell apoptotic process GO:2000353 IMP     actin filament organization GO:0007015 IEA     positive regulation of neuron projection development GO:0010976 IMP     negative regulation of apoptotic process GO:0043066 TAS     bicellular tight junction assembly GO:0070830 TAS     Golgi vesicle budding GO:0048194 IEA     positive regulation of NF-kappaB transcription factor activity GO:0051092 IDA     cell-cell junction organization GO:0045216 TAS     neurotrophin TRK receptor signaling pathway GO:0048011 TAS     protein phosphorylation GO:0006468 IDA     eye photoreceptor cell development GO:0042462 IEA     secretion GO:0046903 NAS     membrane organization GO:0061024 NAS     negative regulation of glial cell apoptotic process GO:0034351 IMP     vesicle-mediated transport GO:0016192 TAS     cellular response to insulin stimulus GO:0032869 ISS     cell junction assembly GO:0034329 TAS     positive regulation of establishment of protein localization to plasma membrane GO:0090004 ISS     positive regulation of glial cell proliferation GO:0060252 IMP     cell migration GO:0016477 IEA     positive regulation of glucose import GO:0046326 ISS     negative regulation of neuron apoptotic process GO:0043524 IDA Subcellular Localization     cytoplasm GO:0005737 IDA     Golgi membrane GO:0000139 IEA     bicellular tight junction GO:0005923 IEA     extracellular exosome GO:0070062 IDA     cell leading edge GO:0031252 IEA     intercellular bridge GO:0045171 IDA     nucleus GO:0005634 IDA     protein complex GO:0043234 IEA     microtubule cytoskeleton GO:0015630 IDA     apical plasma membrane GO:0016324 IEA     endosome GO:0005768 IEA     Schmidt-Lanterman incisure GO:0043220 IEA     cytosol GO:0005829 TAS     plasma membrane GO:0005886 TAS