Gene description for TJP1
Gene name	tight junction protein 1
Gene symbol	TJP1
Other names/aliases	ZO-1
Species	Homo sapiens
Database cross references - TJP1
ExoCarta	ExoCarta_7082
Entrez Gene	7082
HGNC	11827
MIM	601009
UniProt	Q07157
TJP1 identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells	23333927
Ovarian cancer cells	23333927
Prostate cancer cells	25844599

Gene ontology annotations for TJP1

Molecular Function     protein C-terminus binding GO:0008022 IEA     calmodulin binding GO:0005516 IEA     protein binding GO:0005515 IPI     protein domain specific binding GO:0019904 IEA Biological Process     hippo signaling GO:0035329 TAS     response to magnetism GO:0071000 IEA     programmed cell death GO:0012501 TAS     sensory perception of sound GO:0007605 IEA     establishment of endothelial intestinal barrier GO:0090557 IMP     cell-cell junction assembly GO:0007043 TAS     blastocyst formation GO:0001825 IEA     membrane organization GO:0061024 TAS     negative regulation of vascular permeability GO:0043116 IEA     cellular component disassembly involved in execution phase of apoptosis GO:0006921 TAS     response to drug GO:0042493 IEA     cell-cell signaling involved in cell-cell junction organization GO:1901350 NAS     cellular response to glucose stimulus GO:0071333 IEA     response to ethanol GO:0045471 IEA     response to lipopolysaccharide GO:0032496 IEA     apoptotic process GO:0006915 TAS Subcellular Localization     basolateral plasma membrane GO:0016323 IDA     plasma membrane GO:0005886 TAS     cytosol GO:0005829 TAS     bicellular tight junction GO:0005923 IDA     intercellular canaliculus GO:0046581 IEA     cell-cell adherens junction GO:0005913 IEA     cytoplasm GO:0005737 IDA     intercalated disc GO:0014704 IEA     apical junction complex GO:0043296 IDA     apical plasma membrane GO:0016324 IEA     nucleus GO:0005634 IEA     cell junction GO:0030054 IDA     gap junction GO:0005921 IEA     apicolateral plasma membrane GO:0016327 IEA     apical part of cell GO:0045177 IDA