Gene description for VMP1
Gene name vacuole membrane protein 1
Gene symbol VMP1
Other names/aliases EPG3
TANGO5
TMEM49
Species Homo sapiens
 Database cross references - VMP1
ExoCarta ExoCarta_81671
Entrez Gene 81671
HGNC 29559
MIM 611753
UniProt Q96GC9  
 VMP1 identified in exosomes derived from the following tissue/cell type
Endothelial cells 26027894    
 Gene ontology annotations for VMP1
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    exocytosis GO:0006887 IBA
    regulation of autophagy GO:0010506 ISS
    Golgi organization GO:0007030 IBA
    embryo implantation GO:0007566 IEA
    autophagy GO:0006914 IEA
    single organismal cell-cell adhesion GO:0016337 IMP
    endoplasmic reticulum organization GO:0007029 IBA
    cell junction assembly GO:0034329 IMP
Subcellular Localization
    autophagosome membrane GO:0000421 ISS
    plasma membrane GO:0005886 IEA
    endoplasmic reticulum GO:0005783 IDA
    endomembrane system GO:0012505 IBA
    endoplasmic reticulum-Golgi intermediate compartment membrane GO:0033116 IEA
    pre-autophagosomal structure GO:0000407 IBA
    integral component of membrane GO:0016021 IEA
    membrane GO:0016020 IBA
 Experiment description of studies that identified VMP1 in exosomes
1
Experiment ID 226
ISEV standards
EM
EV Biophysical techniques
GAPDH
EV Cytosolic markers
CD9|FLOT1
EV Membrane markers
LMNA|H2AFX|ATP5A1|TOMM20
EV Negative markers
EV Particle analysis
Identified molecule mRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting
Authors Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
 Protein-protein interactions for VMP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which VMP1 is involved
No pathways found





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