Gene description for ANGPT1
Gene name	angiopoietin 1
Gene symbol	ANGPT1
Other names/aliases	AGP1 AGPT ANG1
Species	Homo sapiens
Database cross references - ANGPT1
ExoCarta	ExoCarta_284
Entrez Gene	284
HGNC	484
MIM	601667
UniProt	Q15389
ANGPT1 identified in exosomes derived from the following tissue/cell type
Platelets	25332113
Platelets	25332113
Platelets	25332113
Saliva	19199708

Gene ontology annotations for ANGPT1

Molecular Function     protein binding GO:0005515 IPI     receptor tyrosine kinase binding GO:0030971 IPI Biological Process     sprouting angiogenesis GO:0002040 IDA     positive regulation of endothelial cell migration GO:0010595 IDA     positive regulation of cell adhesion GO:0045785 IEA     regulation of satellite cell proliferation GO:0014842 IDA     activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 IDA     negative regulation of vascular permeability GO:0043116 IDA     positive regulation of ERK1 and ERK2 cascade GO:0070374 IDA     negative regulation of neuron apoptotic process GO:0043524 IEA     cell-substrate adhesion GO:0031589 IEA     positive regulation of receptor internalization GO:0002092 IDA     positive regulation of phosphatidylinositol 3-kinase signaling GO:0014068 IEA     protein localization to cell surface GO:0034394 IDA     positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 IDA     glomerulus vasculature development GO:0072012 ISS     negative regulation of cytokine secretion involved in immune response GO:0002740 IEA     heparin biosynthetic process GO:0030210 IDA     blood coagulation GO:0007596 TAS     regulation of endothelial cell proliferation GO:0001936 IDA     negative regulation of protein phosphorylation GO:0001933 IEA     positive regulation of protein kinase B signaling GO:0051897 IDA     in utero embryonic development GO:0001701 IEA     cell differentiation GO:0030154 IEA     negative regulation of apoptotic process GO:0043066 IDA     positive regulation of protein ubiquitination GO:0031398 IDA     regulation of protein binding GO:0043393 IEA     Tie signaling pathway GO:0048014 IDA     hemopoiesis GO:0030097 IEA     regulation of I-kappaB kinase/NF-kappaB signaling GO:0043122 IEA     leukocyte migration GO:0050900 TAS     negative regulation of endothelial cell apoptotic process GO:2000352 IDA     positive regulation of blood vessel endothelial cell migration GO:0043536 IDA     positive chemotaxis GO:0050918 IDA     regulation of macrophage migration inhibitory factor signaling pathway GO:2000446 IEA     negative regulation of cell adhesion GO:0007162 IDA     negative regulation of protein import into nucleus GO:0042308 IEA     positive regulation of peptidyl-serine phosphorylation GO:0033138 IEA     regulation of tumor necrosis factor production GO:0032680 IEA Subcellular Localization     microvillus GO:0005902 IDA     extracellular space GO:0005615 IDA     plasma membrane GO:0005886 IDA     extracellular region GO:0005576 TAS     membrane raft GO:0045121 IDA     extracellular exosome GO:0070062 IDA