Gene description for CLDN5
Gene name	claudin 5
Gene symbol	CLDN5
Other names/aliases	AWAL BEC1 CPETRL1 TMVCF
Species	Homo sapiens
Database cross references - CLDN5
ExoCarta	ExoCarta_7122
Vesiclepedia	VP_7122
Entrez Gene	7122
HGNC	2047
MIM	602101
UniProt	O00501
CLDN5 identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells	19619303
Platelets	25332113
Platelets	25332113
Platelets	25332113

Gene ontology annotations for CLDN5

Molecular Function     structural molecule activity GO:0005198 IEA     protein binding GO:0005515 IPI     identical protein binding GO:0042802 ISS Biological Process     outflow tract morphogenesis GO:0003151 TAS     cell-cell junction assembly GO:0007043 IMP     cell adhesion GO:0007155 IBA     transforming growth factor beta receptor signaling pathway GO:0007179 IDA     learning GO:0007612 TAS     positive regulation of cell population proliferation GO:0008284 IMP     positive regulation of gene expression GO:0010628 IMP     positive regulation of gene expression GO:0010628 ISS     negative regulation of gene expression GO:0010629 IMP     negative regulation of gene expression GO:0010629 ISS     calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules GO:0016338 ISS     negative regulation of angiogenesis GO:0016525 IMP     negative regulation of cell migration GO:0030336 IMP     positive regulation of protein binding GO:0032092 IMP     maintenance of blood-brain barrier GO:0035633 IMP     maintenance of blood-brain barrier GO:0035633 NAS     myelination GO:0042552 IEA     negative regulation of vascular permeability GO:0043116 IMP     response to ethanol GO:0045471 IEA     roof of mouth development GO:0060021 TAS     face morphogenesis GO:0060325 TAS     bicellular tight junction assembly GO:0070830 IBA     tight junction assembly GO:0120192 ISS     positive regulation of establishment of endothelial barrier GO:1903142 IMP     positive regulation of bicellular tight junction assembly GO:1903348 IMP     establishment of blood-retinal barrier GO:1990963 IMP Subcellular Localization     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 IDA     cell-cell junction GO:0005911 IDA     cell-cell junction GO:0005911 IMP     bicellular tight junction GO:0005923 IBA     bicellular tight junction GO:0005923 IDA     bicellular tight junction GO:0005923 ISS     membrane GO:0016020 NAS     membrane GO:0016020 TAS     apicolateral plasma membrane GO:0016327 IDA     lateral plasma membrane GO:0016328 IEA     cell junction GO:0030054 TAS     cortical actin cytoskeleton GO:0030864 IDA     paranode region of axon GO:0033270 IEA     Schmidt-Lanterman incisure GO:0043220 IEA     tight junction GO:0070160 IDA