Gene description for DUSP23
Gene name dual specificity phosphatase 23
Gene symbol DUSP23
Other names/aliases DUSP25
LDP-3
MOSP
VHZ
Species Homo sapiens
 Database cross references - DUSP23
ExoCarta ExoCarta_54935
Vesiclepedia VP_54935
Entrez Gene 54935
HGNC 21480
UniProt Q9BVJ7  
 DUSP23 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
 Gene ontology annotations for DUSP23
Molecular Function
    protein tyrosine phosphatase activity GO:0004725 IEA
    protein binding GO:0005515 IPI
    protein tyrosine/serine/threonine phosphatase activity GO:0008138 IEA
Biological Process
    peptidyl-tyrosine dephosphorylation GO:0035335 IEA
Subcellular Localization
    extracellular exosome GO:0070062 IDA
    cytosol GO:0005829 IEA
    nucleus GO:0005634 IEA
 Experiment description of studies that identified DUSP23 in exosomes
1
Experiment ID 488
MISEV standards
✔
EM
EV Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
EV Enriched markers
✔
CANX
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for DUSP23
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which DUSP23 is involved
No pathways found





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