Gene description for AAAS
Gene name achalasia, adrenocortical insufficiency, alacrimia
Gene symbol AAAS
Other names/aliases AAA
AAASb
ADRACALA
ADRACALIN
ALADIN
GL003
Species Homo sapiens
 Database cross references - AAAS
ExoCarta ExoCarta_8086
Entrez Gene 8086
HGNC 13666
MIM 605378
UniProt Q9NRG9  
 AAAS identified in exosomes derived from the following tissue/cell type
Urine 22418980    
Urine 22418980    
 Gene ontology annotations for AAAS
Molecular Function
    molecular_function GO:0003674 ND
Biological Process
    regulation of cellular response to heat GO:1900034 TAS
    hexose transport GO:0008645 TAS
    carbohydrate metabolic process GO:0005975 TAS
    fertilization GO:0009566 IEA
    cytokine-mediated signaling pathway GO:0019221 TAS
    cellular response to heat GO:0034605 TAS
    cellular protein metabolic process GO:0044267 TAS
    post-translational protein modification GO:0043687 TAS
    protein transport GO:0015031 IEA
    glucose transport GO:0015758 TAS
    viral life cycle GO:0019058 TAS
    protein sumoylation GO:0016925 TAS
    viral transcription GO:0019083 TAS
    regulation of nucleocytoplasmic transport GO:0046822 NAS
    transmembrane transport GO:0055085 TAS
    viral process GO:0016032 TAS
    nucleocytoplasmic transport GO:0006913 IDA
    learning GO:0007612 IEA
    regulation of glucose transport GO:0010827 TAS
    gene expression GO:0010467 TAS
    mitotic nuclear envelope disassembly GO:0007077 TAS
    mitotic cell cycle GO:0000278 TAS
    small molecule metabolic process GO:0044281 TAS
    mRNA transport GO:0051028 IEA
Subcellular Localization
    nuclear membrane GO:0031965 IDA
    nuclear envelope GO:0005635 TAS
    membrane GO:0016020 IDA
    nuclear pore GO:0005643 IDA
    cytoplasm GO:0005737 IDA
    nucleus GO:0005634 IDA
    centrosome GO:0005813 IDA
    nucleoplasm GO:0005654 IDA
 Experiment description of studies that identified AAAS in exosomes
1
Experiment ID 196
ISEV standards
EM
EV Biophysical techniques
Alix|TSG101|HSP70
EV Cytosolic markers
CD9
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors Raj DA, Fiume I, Capasso G, Pocsfalvi G.
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal high density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 197
ISEV standards
EM
EV Biophysical techniques
Alix|TSG101|HSP70
EV Cytosolic markers
CD9
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors Raj DA, Fiume I, Capasso G, Pocsfalvi G.
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal low density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for AAAS
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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