Gene description for EMP3
Gene name epithelial membrane protein 3
Gene symbol EMP3
Other names/aliases YMP
Species Homo sapiens
 Database cross references - EMP3
ExoCarta ExoCarta_2014
Vesiclepedia VP_2014
Entrez Gene 2014
HGNC 3335
MIM 602335
UniProt P54852  
 EMP3 identified in exosomes derived from the following tissue/cell type
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
 Gene ontology annotations for EMP3
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    cell death GO:0008219 IDA
    cell growth GO:0016049 IEA
    bleb assembly GO:0032060 IDA
    negative regulation of cell proliferation GO:0008285 TAS
Subcellular Localization
    plasma membrane GO:0005886 IDA
    integral component of membrane GO:0016021 IEA
 Experiment description of studies that identified EMP3 in exosomes
1
Experiment ID 834
MISEV standards
✔
EM
EV Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
EV Enriched markers
✔
CANX
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 835
MISEV standards
✔
EM
EV Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
EV Enriched markers
✔
CANX
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for EMP3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CALM3 808
Invivo Homo sapiens
Invitro Homo sapiens
Two-hybrid Homo sapiens
2 CALM2 805
Invivo Homo sapiens
Invitro Homo sapiens
Two-hybrid Homo sapiens
3 CALM1 801
Invivo Homo sapiens
Invitro Homo sapiens
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which EMP3 is involved
No pathways found





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