Gene description for SECTM1
Gene name secreted and transmembrane 1
Gene symbol SECTM1
Other names/aliases K12
Species Homo sapiens
 Database cross references - SECTM1
ExoCarta ExoCarta_6398
Entrez Gene 6398
HGNC 10707
MIM 602602
UniProt Q8WVN6  
 SECTM1 identified in exosomes derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for SECTM1
Molecular Function
    cytokine activity GO:0005125 TAS
    signal transducer activity GO:0004871 IMP
Biological Process
    mesoderm development GO:0007498 TAS
    immune response GO:0006955 TAS
    positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 IMP
    signal transduction GO:0007165 IMP
Subcellular Localization
    Golgi apparatus GO:0005794 TAS
    extracellular exosome GO:0070062 IDA
    plasma membrane GO:0005886 IEA
    integral component of membrane GO:0016021 IDA
    extracellular space GO:0005615 TAS
 Experiment description of studies that identified SECTM1 in exosomes
1
Experiment ID 63
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
AQP2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for SECTM1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CD7  
Invivo Homo sapiens
Invitro Homo sapiens
View the network image/svg+xml
 Pathways in which SECTM1 is involved
No pathways found





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